Ototoxic Drugs: Drugs That Cause Tinnitus

Discussion in 'Support' started by calin, Jun 18, 2012.

    1. calin

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      These drugs are listed in the Physicians Daily Reference as causing tinnitus as a side effect. This information is provided as a service and you are advised to check the product literature supplied with the medications you are on.

      Abelcet Injection (Liposome)
      Accutane Capsules
      Aceon Tablets (2 mg, 4 mg, 8 mg)
      Aciphex Tablets
      Acromycin V
      Actifed with Codiene Cough Syrup
      Actiq (Anesta)
      Actonel Tablets
      Adalat CC
      Aggrenox Capsules
      Agrylin Capsules
      Alferon N Injection (Interferon)
      Alka-Seltzer Original Antacid and Pain Reliever Effervescent Tablets
      Alka-Seltzer Cherry Antacid and Pain Reliever Effervescent Tablets
      Alka-Seltzer Lemon Lime Antacid and Pain Reliever Effervescent Tablets
      Alka-Seltzer Extra Strength Antacid and Pain Reliever Effervescent Tablets
      Alka-Seltzer PM Effervescent Tablets
      Alferon N
      Alumadrine Tablets
      Alumadrine Tablets
      Amerge Tablets
      Anaprox and Anaprox DS
      Anzemet Injection
      Anzemet Tablets
      Aralen Injection
      Aralen Tablets
      Arithritis Strength BC Powder
      Aricept Tablets
      Aricept Tablets
      Arthrotec Tablets
      Ascriptin A/D
      Atacand HCT Tablets
      Atrovent Nasal Spray
      Atrohist Plus
      Avelox Tablets
      Azactam Tablets
      Azactam for Injection
      Azo Gantanol
      Azo Gantrisin
      Azulfidine EN-tabs Tablet
      BC Powder
      Bactrim DS
      Bactrim I.V.
      Arthritis Strength BC Powder
      Benadryl Parenteral
      Betaxon Ophthalmic Suspension
      Biaxin Filmtab Tablets
      Biaxin for Oral Suspension
      Biaxin XL Filmtab Tablets
      Bicillin L-A Injection
      Buprenex Injectable
      Calan Tablets
      Calan SR Caplets
      Capastat Sulfate
      Carbocaine Hydrochloride
      Carbatrol Capsules
      Celebrex Capsules
      Celebrex Capsules
      Celexa Oral Suspension
      Celexa Tablets
      CellCept Capsules
      CellCept Intravenous
      CellCept Oral Suspension
      CellCept Tablets
      Cerebyx Injection
      Chibroxin Sterile Ophthalmic Solution
      Childrens Advil
      Cipro I.V.
      Cipro Tablets
      Cipro Oral Suspension
      Claritin Reditabs
      Claritin Syrup
      Claritin Tablets
      Claritin-D 12 Hour Extended Release Tablets
      Claritin-D 24 Hour Extended Release Tablets
      Clomid Tablets
      Cognex Capsules
      Colazal Capsules
      Copaxone for Injection
      Coreg Tablets
      Cosopt Sterile Ophthalmic Solution
      Covera-HS Tablets
      Cozaar Tablets
      Cytovene Capsules
      Dapsone USP
      Daranide Tablets
      DaunoXome Injection
      Depacon Injection
      Depakene Capsules
      Depakene Syrup
      Depakote Sprinkle Capsules
      Depakote Tablets
      Depakote ER Tablets
      Depen Titratable Tablets
      Desferal Vials
      Desyrel & Desyrel Dividose
      Diamox Intravenous
      Diamox Sequels Sustained Release Capsules
      Diamox Tablets
      Diovan HCT Tablets
      Dilacor XR
      Dipentum Capsules
      Disalcid Capsules
      Disalcid Tablets
      Dolobid Tablets
      Doxil Injection
      Duraclon Injection
      Duranest Injections
      Dynabac Tablets
      Dyphenhydramine [Nytol, Benydrl, etc]
      Effexor Tablets
      Effexor XR Capsules
      ELA-Max Cream
      Emla cream
      Empirin with Codiene
      EtrafonEvoxac Capsules
      Excedrin Extra-Strength Tablets, Caplets, and Geltabs
      Exelon Capsules
      Exelon Oral Solution
      Feldene Capsules
      Fioricat with Codeine
      Flexeril Tablets
      Flumadine Syrup
      Flumadine Tablets
      Fortovase Capsules
      Furosemide Tablet
      Gabitril Filmtab Tablets
      Gastrocrom Oral Concentrate
      Gengraf Capsules
      Geodon Capsule
      HIVID Tablets
      Halcion Tablets
      Hytrin Capsules
      Hyzaar 50-12.5 Tablets
      Hyzaar 100-25 Tablets
      Imitrex Nasal Spray
      Indocin Capsules
      Indocin Oral Suspension
      Indocin Suppositories
      Intron A
      Invirase Capsules
      Isoptin SR Tablets
      Kerlone Tablets
      Lamictal Tablets
      Lamictal Chewable
      Levaquin Injection
      Levaquin Tablets
      Lexxel Tablets
      Lidoderm Patch
      Lipitor Tablets
      Lipitor Tablets
      Lithium Carbonate
      Lithobid Slow-Release Tablets
      Lodine Capsules
      Lodine Tablets
      Lodine XL Extended-Release Tablets
      Lopressor Ampuis
      Lopressor DCT
      Lotensin HCT Tablets
      Lotrel Capsules
      Lupron Depot
      Luvox Tablets
      Marinol (Dronabinol)
      Marcaine Hydrochloride
      Marcaine Spinal
      Maxalt Tablets
      Maxalt-MLT Orally Disintegrating Tablets
      Maxaquin Tablets
      Marcaine Hydrochloride
      Marcaine Spinal
      Meridia Capsules
      Mexitil Capsules
      Miacalcin Nasal Spray
      Micardis HCT Tablets
      Micardis Tablets
      Midamor Tablets
      Migranal Nasal Spray
      Minipress Capsules
      Minizide Capsules
      Mintezol Suspension
      Mintezol Chewable Tablets
      Mirapex Tablets
      Mobic Tablets
      Moduretic Tablets
      Momentum Backache Relief Extra Strength Caplets
      Monopril Tablets
      Motrin Suspension, Oral Drops, Chewable Tablets
      Mustargen for Injection
      Mykrox Tablets
      Myobloc Injectable Solution
      Nalfon Capsules
      Nadolol Tablets
      Naprelan Tablets
      Naprosyn Suspension
      Naprosyn Tablets
      Naropin Injection
      Nebcin Vials, Hyporets & ADD-Vantage
      Neoral Soft Gelatin Capsules
      Neoral Oral Solution
      Neptazane Tablets
      Nescaine Injection
      Nesacaine-MPF Injection
      Neurontin Capsules
      Neurontin Oral Solution
      Neurontin Tablets
      Nexium Delayed-Release Capsules
      Nipent for Injection
      Nipent for Injection
      Noroxin Tablets
      Norpramin Tablets
      Norvasc Tablets
      Norvir Capsules
      Norvir Oral Solution
      Omniscan [less than 1%]
      Ornade Spansule Capsules
      Orthoclone OOKT3 Sterile Solution
      Orudis Capsules
      Oruvail Capsules
      OxyContin Tablets
      P-A-C Analgesic
      Parnate Tablets
      Paxil Oral Suspension
      Paxil Tablets
      Pediazole Suspension
      Penetrex Tablets
      Pepcid Injection
      Pepcid Injection Premixed
      Pepcid for Oral Suspension
      Pepcid RPD Orally Disintegrating Tablets Pepcid Tablets
      Pepto-Bismol Maximum Strength Liquid
      Pepto-Bismol Original Liquid, Original and Cherry Tablets and Easy-To-Swallow Caplets
      Periactin Tablets
      Permax Tablets
      Phenergan Injection
      Phenergan Suppositories
      Phenergan Tablets
      Phrenilin Forte Capsules
      Phrenilin Tablets
      Piroxicam [1-3%]
      Plaquenil Tablets
      Platinol-AQ Injection
      Pletal Tablets
      Pletal Tablets
      Polocaine Injection, USP
      Polocaine-MPF Injection, USP
      Pontocaine Hydrochloride
      Ponstel Kapseals
      Prilosec Delayed-Release Capsules
      Primaxin I.M.
      Primaxin I.V.
      Prevacid Delayed-Release Capsules
      Prinivil Tablets
      Prinzide Tablets
      Procardia Capsules
      Procardia Tablets
      Protonix Tablets
      Proventil HFA Inhalation Aerosol
      Proventil Repetabs Tablets
      Proventil Tablets
      Prozac Pulvules & Liquid, Oral Solution
      Prozac Pulvules, Liquid, and Weekly Capsules
      Quinaglute Dura-Tabs Tablets
      Quinidex Extentabs
      Quinidine Gluconate Injection, USP
      Q-vel Muscle Relaxant Pain Reliever
      Rapamune Oral Solution and Tablets
      Recombivax HB
      Relafen Tablets
      Rheumatrex Methotrexate
      Requip Tablets
      Rescriptor Tablet
      ReVia Tablets
      Risperdal Oral Solution
      Risperdal Tablets
      Romazicon Injection
      Rynatan Tablets
      Rythmol Tablets
      Salagen Tablets
      Sandimmune I.V. Ampuls for Infusion
      Sandimmune Oral Solution
      Sandimmune Soft Gelatin Capsules
      Sandostatin LAR Depot
      Sarafem Pulvules
      Sedapap Tablets
      Sensorcaine Injection
      Sensorcaine with Epinephrine Injection
      Sensorcaine-MPF Injection
      Sensorcaine-MPF with Epinephrine Injection
      Septra I.V. Infusion
      Septra Suspension
      Septra Grape Suspension
      Septra Tablets
      Septra DS Tablets
      Seroquel Tablets
      Serzone Tablets
      Sinequan Capsules
      Sinequan Oral
      Soma Compound Tablets
      Soma Compound w/Codeine Tablets
      Sonata Capsules
      Soriatane Capsules
      Sporanox Capsules
      Sporanox Oral Solution
      Sporanox Oral Solution
      Stadol NS Nasal Spray
      Streptomycin Sulfate
      Sular Tablets
      Surmontil Capsules
      Sustiva Capsules
      Talacen Caplets
      Talwin Compound Caplets
      Talwin Nx Tablet
      Tambocor Tablets
      Tarka Tablets
      Tasmar Tablets
      Tavist and Tavist-D
      Tegretol Chewable Tablets
      Tegretol Suspension
      Tegretol Tablets
      Tegretol-XR Tablets
      Tenex Tablets
      Teveten Tablets
      Tequin Injection
      Tequin Tablets
      Thalomid Capsules
      Thiosulfil Forte
      Tiazac Capsules
      Ticlid Tablets
      Timolide Tablets
      Timoptic in Ocudose
      Timoptic Sterile Ophthalmic Solution
      Timoptic-XE Sterile Ophthalmic Gel Forming Solution
      TOBI Solution for Inhalation
      Tolectin 200 Tablets
      Tolectin 600 Tablets
      Tolectin DS Capsules
      Tonocard Tablets
      Topamax Sprinkle Capsules
      Topamax Tablets
      Toprol XL Tablets
      Toradol IM Injection, IV Injection
      Toradol Tablets
      Tricor Capsules, Micronized
      Trileptal Tablets
      Trilisate Liquid
      Trilisate Tablets
      Trinalin Repetabs
      Trisenox Injection
      Trovan I.V.
      Trovan Tablets
      Tussend Syrup
      Tussend Tablets
      Tympagesic Ear Drops
      Ultram Tablets
      Uniretic Tablets
      Univasc Tablets
      Vancocin HCI
      Vancenase AQ Double Strength Nasal Spray 0.084%
      Vancocin HCl Capsules & Pulvules
      Vancocin HCl Oral Solution
      Vancocin HCl, Vials & ADD-Vantage
      Vantin Tablets and Oral Suspension
      Vascor Tablets
      Vaseretic Tablets
      Vasotec I.V. Injection
      Vasotec Tablets
      Verelan Capsules
      Verelan PM Capsules
      Viagra Tablets
      Vicoprofen Tablets
      Vioxx Oral Suspension
      Vioxx Tablets
      Vistide Injection
      Vivactil Tablets
      Voltaren Tablets
      Voltaren-XR Tablets
      Wellbutrin Tablets
      Wellbutrin SR Sustained-Release Tablet
      Xanax Tablets
      Xylocaine Injection
      Xylocaine with Epinephrine Injection
      Zagam Tablets
      Zanaflex Tablets
      Zebeta Tablets
      Zestoretic Tablet
      Zestril Tablets
      Zestoretic [0.3-1%]
      Ziac Tablets
      Zithromax Capsules, 250 mg
      Zithromax for IV Infusion
      Zithromax for Oral Suspension, 300 mg, 600 mg, 900 mg, 1200 mg
      Zithromax Tablets, 250 mg
      Zoloft Oral Concentrate
      Zoloft Tablets
      Zomig Tablets
      Zomig-ZMT Tablets
      Zonegran Capsules
      Zyban Sustained-Release Tablets
      Zyprexa Tablets
      Zyprexa ZYDIS Orally Disintegrating Tablets
      Zyrtec Syrup
      Zyrtec Tablet
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    2. erik

      erik Member Benefactor Hall of Fame

      Washington State, USA
      Tinnitus Since:
      04/15/2012 or earlier?
      Cause of Tinnitus:
      Most likely hearing loss
      Good list although it is missing drugs such as the Benzos: Valium, Ativan, etc and some of the Antihistamines like Citrizine in which all the H1 Blocker over the counter 3rd Gen drugs are Ototoxic. Even things like Vicks vapor rub with camphor is ototoxic and most cortisone creams.
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    3. AUTHOR

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      Yea... my beta blockers which I don't take any more are under Lopressor - not metaprolol...

      Thanks erik!
    4. dawne'ne

      dawne'ne Member

      Lake Stevens, Washington
      Tinnitus Since:
      calin, i've been reading all your blogs and find all your info. really helpful. i just started my journey with this illness all i'm taking is ring stop and it's helping. i 'm making an appt. with an ear throat doc . this next week!
    5. AUTHOR

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      Hi dawne'ne! Nice to meet you!

      What is in ring stop? Can you give a bit more on how it has helped you? Lower T sound?

      And, do you have pulsing tinnitus or regular (haha - whatever that means!)
    6. AUTHOR

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      There are about a thousand drugs/products that are Oto-Toxic (oto means hearing). Any or a combination could have caused your tinnitus.

      Here is a short list...

      Ototoxic Drugs

      The following list contains drugs that can have a temporary or permanent effect on hearing such as hearing loss or tinnitus.
      They were identified through the reading of Dr. Susan Kunkel from the Poison Center at the University of New Mexico College of Pharmacy where she is a Toxicology Fellow.

      Please note that this is not an all-inclusive list of every ototoxic drug nor an exhaustive list of all drugs in each category.

      The few that are especially important are displayed in bold.

      Some drugs have more than one use and/or may fit into more than one category.
      Certain non-drug substances (e.g., various metals, chemicals and asphyxiant gases) as well as noise have been associated with hearing loss.

      In some cases, the medications listed can cause hearing changes even at regular doses.
      Nonetheless higher-than-recommended doses are never a good idea and this practice would certainly increase risk of changes in hearing.
      Users of these (or any other drugs) are advised to not exceed recommended dosages and to ask your doctor or pharmacist specifically if there are any potential ototoxic effects associated with any new drug or over-the-counter medication you are told to take.

      tp.gif NOTE: Anyone reviewing this list of ototoxic drugs is strongly advised NOT to discontinue taking any prescribed medication without first contacting the prescribing physician.

      Ototoxic Drugs by Category, with Examples


      Aminoglycosides (amikacin, gentamicin, tobramycin…)
      Amphotericin B
      tp.gif Antihelminthics (Praziquantel, thiabendazole)
      tp.gif Chloramphenicol
      tp.gif Chlorhexidine (for topical use)
      tp.gif Colistin
      Griseofulvin (antifungal)
      Macrolides (azithromycin, erythromycin)
      Nalidixic acid
      Tetracyclines (Minocycline, tetracycline)
      Thiabenzazole (antihelmintic)

      Anti-inflammatory agents (NSAIDs, salicylates)

      Aspirin (salicylic acid)

      Antineoplastic agents

      Methotrexate (also for RA)
      Nitrogen mustard

      Cardiovascular agents

      Minoxidil (also for alopecia)


      Ethacrynic acid

      Tricyclic antidepressants


      Substances with abuse potential

      Phencyclidine (PCP)

      Miscellaneous agents

      Carbamazepine (anticonvulsant)
      Hydroquinone (antipigmentation agent)
      Local anesthetics (Bupivacaine, lidocaine, mepivacaine)
      Metal chelators (Deferoxamine, penicillamine)
      Oral contraceptives

      Added by Tinnitus Talk's administrative team:
      Please register to Tinnitus Talk. It is free. We are a nice group of knowledgeable individuals and you will certainly benefit becoming one of us.
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    7. mock turtle

      mock turtle Member

      puget sound
      Tinnitus Since:
      07/26/1992...habituated after 2 years; 11/04/11 new outbreak
      calin, thanks for the list

      yep its very important that people be aware and check to see if drugs...medications ...pose a significant risk of tinnitus

      i would almost be willing to venture a guess that more drugs are ototoxic, than not !

      (sure feels that way)

      best wishes
    8. Karen

      Karen Manager Staff Benefactor Ambassador Hall of Fame

      Tinnitus Since:
      Cause of Tinnitus:
      First time: Noise 2nd Time: Ototoxic drug
      Thanks, Calin. I feel sure that blood pressure drugs caused my severe tinnitus, although they are not on the list. I agree with Mock Turtle; before you take any new drug, please do check to see if it is ototoxic, and see there might be a substitute you can take that does not harm your ears.
    9. Fish

      Fish Member Benefactor

      Tinnitus Since:
      July 2012
      This is only a partial list. I cannot find it anymore but there was an article on American Tinnitus Association website about ototoxic drugs and there have been really many of them!

      Among the ototoxic drugs I used are:

      possibly ototoxic:

      - ibuprofen
      - H2 blocker
      - pantoprazole ("proton pump inhibiotor" type of drugs)

      highly ototoxic and neurotoxic:

      - ciprofloxacin ("fluoroquinolone" type antibiotic)

      This has taught me a lesson to be very careful and never take any drugs unless my life would depend on it!
    10. erik

      erik Member Benefactor Hall of Fame

      Washington State, USA
      Tinnitus Since:
      04/15/2012 or earlier?
      Cause of Tinnitus:
      Most likely hearing loss
      Pretty much everything can be ototoxic, even things like Vicks Vapor Rub which has camphor in it which is also on the ototoxic list. 84 of the top 100 prescribed medications are thought be ototoxic in some capacity. But we have to keep in mind that most of the ototoxic effects are dose related. Ototoxicity with NSaids for example are almost dose related and almost always reversible once stopped. If you need Tylenol or Ibuproferin, just don't max out on dosage for a long period of time.
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    11. Karl

      Karl Member Benefactor

      Tinnitus Since:
      How about water?

      I think there should be a new classification of drugs that excite the auditory nerves as opposed to killing the cochlear hair cells. For too long, people have been mixing up drugs that make their tinnitus seem louder and drugs that actually cause serious damage.

      Coffee can excite the nervous system, making tinnitus louder. Some people say Zoloft can be make it louder, but that's temporary. Asprin can cause tinnitus, but that's temporary. The nervous system can get excited, making tinnitus seem louder.

      Certain antibiotics truly do damage to the cochlear hair cells - that's ototocity.
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    12. Thomas

      Thomas Guest

      thank you so much....that is the most logical explanation i have heard....things like antibiotics and chemotherapy drugs are designed with the intent to kill and therefore, it seems logical that they would destroy cochlear hair cells, but you're right it wouldn't make sense that they would cause hearing loss...but how do you feel about the stories regarding hearing loss after taking Amitriptyline? i also find it funny that people say that aspirin is ototoxic...aspirin is broken down in the body into salicylic acid which is nature's anti-inflammatory...if you drink enough orange juice you can achieve the same effect
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    13. Sybs

      Sybs Member

      Tinnitus Since:
      I have been on Zoloft for over 3 years but only just started getting Tinnitus a few weeks ago. My doctor seems to think that the side effect could have just appeared after all this time (I am not convinced), so she has asked me to come off them. I was on 50mg and for the last week have been on 25mg. And now she wants me to go to 25mg ever other day before coming off them completely. Do you think she could be right?
    14. Louise

      Louise Member Benefactor

      Yorkshire, UK
      Tinnitus Since:
      29/06/2012 worsened Jan 2017 & Dec 2017
      Cause of Tinnitus:
      Noise exposure
      Hi Sybs,

      It's a tough one to answer. Although, no offence to doctors, I don't think they know anything about tinnitus and virtually nothing about tapering the drugs they freely prescribe.

      Zoloft has been implicated with tinnitus, the same as Prozac has, and a myriad of other drugs. But, 3 years with no problems seems to suggest it's not the culprit? Is there anything else that could be the cause?

      When drugs are reported as ototoxic the question is; is it temporary tinnitus, (and so it will go away if you come of the drug), or has the drug damaged the hearing system. Have you had a hearing test?

      About the tapering - I'd do your own on-line research if I were you. With some drugs, although I'm thinking Benzos here, if you taper too quickly it can actually cause tinnitus.

      All the best,
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    15. mick

      mick Member Benefactor

      Tinnitus Since:
      A few comments based on my reading on the subject over the years:

      1. Aspirin (acetylsalicylic acid) does indeed cause tinnitus at high doses and all evidence indicates that it is reversible and not cumulative. In days of old, arthritis pain was treated by increasing the patient's aspirin dose until their ears began to ring, then the dose was cut back slowly until the ringing stopped. That dose was then the treatment dose for arthritis pain. Whether other NSAIDs like ibuproferen cause reversible or permanant T is debatable. One thing that sets aspirin apart from other NSAIDs is that its effect on platelets is not reversible whereas other NASIDs (with perhaps the exception of naproxen) is reversible. That is why aspirin is safer to take if you are subject to blood clots - platelets exposed to aspirin lose their blood clotting ability for the remainder of their lives while other NSAIDs only temporatily reduce the platelet's ability blood clotting ability. With other NSAIDs there is a rebound effect after the drug's impact on platelet's wears off making the subject more vulnerable to blood clots. Good advice for anyone who has antherosclerosis or who is otherwise predisposed to blood clots is to take aspirin for mild pain relief rather than other NSAIDs. Just pointing out that there is something different about what aspirin does in the body vs other NSAIDs. That something different might explain why aspirin induced T is reversible while that of other NSAIDs may not be.

      2. Based on the theory about excitotoxicity causing T, there is likely a cumulative component to ototoxicity. Excitotoxicity is cumulative and not reversible, thus it is entirely possible that Zoloft could cause T after 3 years of usage. I'm not saying this is what caused Sybs T, only that it is indeed a possibility that should not be shrugged off in any thorough analysis of possible T triggering vectors.

      3. Withdrawal from any drug that impacts brain chemistry seems likely to me to be able to cause T - again because of the possibility of causing excitotoxicity.
    16. Louise

      Louise Member Benefactor

      Yorkshire, UK
      Tinnitus Since:
      29/06/2012 worsened Jan 2017 & Dec 2017
      Cause of Tinnitus:
      Noise exposure
      Thanks Mick.

      Point 2. is not good news at all. It seems to me that once excitotoxicity gets started there's no stopping it. I mean - when does it stop once its rolling?

      Point 3. Yep that's why a gradual taper is safest. But again, even if you dropped it suddenly and got rebound disinhibition and hence excitotoxicity would this then stop? And, if it stops, is it the cell death from the excitotoxicity that actually causes the damage and the T?

      Ps. I took Zoloft for about 4 months years ago after a bereavement and suddenly stopped it - no T.
      PPs. I took Prozac for 3 years after a relationship break-up and tapered it very fast - no T.
      PPPs. I stuck my stupid ear in front of a speaker blaring out rock music for 1.5 hours - T.
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    17. hulagirl

      hulagirl Member

      Las Vegas
      Tinnitus Since:
      What about antihistamines? I'm wondering about Allegra as opposed to Zyrtec or Claritin? If this is already posted somewhere else and I missed it, I apologise. My T has worsened since a dental cleaning and it was the first time I stupidly allowed the girl to use the high pressure water instead of just scraping the old fashioned way. My regular hygienist was gone and this girl didn't want to be bothered doing things the old way. Why was I so stupid!! Makes me never want to get my teeth cleaned again!
    18. mick

      mick Member Benefactor

      Tinnitus Since:
      I don't think your decision to have the high pressure water cleaning was stupid. It was a reasonable decision, and I would venture to guess there are many other decisions you could have made during that time period that could have worsened your T, or that you made earlier in your life that made you more vulnerable to worsened T at that time. Clearly, we can't be expected to make the right choice when we really don't know for sure all the things that can cause T. Don't be quite so hard on yourself or on the hygienist for that matter. Even if the cleaning did worsen you T, I don't think its reasonable, unless you've seen a lot of evidence to the contrary, to expect yourself or the hygienist to know that it would cause you any problems. It's not as if you decided to take up smoking in the face of all the evidence that smoking causes cancer. That kind of choice does warrant the "Why was I so stupid!" treatment.
    19. James
      No Mood

      James Member Benefactor

      Tinnitus Since:
      Pulsing 03/2013
      Have or are you taking any?

      To answer your question,
      Yes, in the past and yes, now.
      Even my medicine is on the list, - Amitriptyline

      I'm been having electric-pulsing-ears all day.
      Quinine? I use to drink gin and tonix.
      Having my wine now, ooohhh

      Anyway, thanks for the lists-
      of things to avoid.
    20. mick

      mick Member Benefactor

      Tinnitus Since:
      I should add to my comment above: I'm not a doctor, and you would be wise to investigate things to your own satisfaction before relying on my advice. That may mean consulting your doctor depending on how much you trust him/her.

      Like all medications, even aspirin has dangerous side effect, some which may be result from cumulative effects. Increased risk of macular degeneration is one recently identified hazard of taking aspirin. I don't think taking an aspirin every now and then is going to significantly increase your risk of AMD, but ... In the end, knowing what is the right thing to do when making decisions about medications (and even how to have your teeth cleaned) is rarely cut and dried. Unfortunately, there's always a lot of ifs and unknowns. Medicine is a complicated world.
    21. Lulubug69

      Lulubug69 Member

      Tinnitus Since:
      I had a recent discussion with a healthcare professional regarding ototoxic drugs.. She explained to me that there are many as we have seen the list at ATA.org, some well known to cause T, some in large doses. She said that any drug that has had even 1 person that got T while using that drug would have to be mentioned as ototoxic. So how does one determine the toxicity of any one drug? And how do we determine the level of danger for using such a drug and at what dose and length of use and how many users actually got T for sure (no other possible factors) from that drug? Do the studies go that in depth?
    22. Riikka

      Riikka Member

      Tinnitus Since:
      At least they do to that extent that in the side effects of a drug is mentioned, if a side effect is common, rare, very rare. A common side effect for example is experienced by between 1 out of 10 and 1 out of 100. I guess the side effects are list according to the experience from clinical trials. Some side effects might be added later.

      So it makes a difference, if tinnitus is a common or a very rare side effect for a drug. If it is very rare, you might think it is more probable that the tinnitus might not be related to taking the drug. Maybe that 1 person out of 100000 that got tinnitus from the drug also listened to loud music? They probably aren't able to exclude all factors that are also influencing the occurrence of a negative health symptom.

      The information included in a drug package doesn't though mention anything about how the dosage effects the occurrence of a side effect. I would guess a larger dosage has always more risks than a smaller one. Some side effects may though only be temporary and pass after for example a couple of weeks. Can anyone explain this?
      • Agree Agree x 1
    23. J M

      J M Member

      Tinnitus Since:
      Dr. Oz had a report on Tylenol (acetaminophen) ototoxicity last year. He said that over time, Tylenol can strip away the protection from your ears and damage them in the long run.

      The last time I took a Tylenol, my right ear shorted out briefly (like a bad speaker connection). No more Tylenol for me, course, your experience may differ.
    24. Dr. Ancill

      Dr. Ancill Member Clinician

      Tinnitus Since:
      There is a lot of nonsense on the Internet about drugs and tinnitus. Most so-called side-effects get on the FDA list simply because they are reported. In most cases, there is no direct evidence that the drug caused tinnitus. In my case, the tinnitus suddenly came on one day and I suppose every medication I was taking could be 'the cause' alth0ugh none of them were. There are clearly drugs that a can cause tinnitus but most of the time the tinnitus will go away as the drug level dissapates. Other drugs, especially some antibiotics and anticancer agents, are truly ototoxic and will cause irreversible damage - fortunately, those drugs are uncommon.
      • Like Like x 2
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      • Informative Informative x 1
    25. J M

      J M Member

      Tinnitus Since:
      Believe it or not, Glipizide (diabetes drug) caused my initial tinnitus. I only took five pills, but I remember a distinct high-pitched ring, and some dizziness, while on the drug. A short time later, I developed a bi-lateral inner ear infection that resulted in tinnitus.
    26. Dr. Ancill

      Dr. Ancill Member Clinician

      Tinnitus Since:
      Why do you assume it was the Glipizide? The initial sympotms could have been the earliest signs of the infection. Diabetes is also a disease of small blood vessels and the blood supply to the inner ear is not immune.
    27. Karen

      Karen Manager Staff Benefactor Ambassador Hall of Fame

      Tinnitus Since:
      Cause of Tinnitus:
      First time: Noise 2nd Time: Ototoxic drug
      I believe you, JM. That's similar to what happened to me, with blood pressure drugs. Every person is different; it could be that our ears were already sensitive, and the drug just set it off. I already had mild tinnitus in my right ear, and after I took the drugs, it was roaring!
    28. Dr. Ancill

      Dr. Ancill Member Clinician

      Tinnitus Since:
      I am reposting this as a new thread as there are so many T sufferers who get into a panic over this issue. Only a few drugs are really ototoxic. Most of the other drugs cause a temporary change, if anything. Remember tinnitus is a symptom, a result of pathology in the brain, so anything that can affect brain chemistry can affect the perception of tinnitus. Many tinnitus sufferers will avoid pharmaceuticals unnecessarily and then expose themselves to over-the-counter 'natural' remedies that have far less quality control and even less safety data. An example of this would be Gingko Biloba which may increase blood flow to the inner ear (in high enough doses) - for many T sufferers this will result in increased tinnitus. The same is true for Flavinoids. However, forum watchers will know that from time to time, someone will post a remedy that worked for them. This might simply be coincidence but sometimes it is a genuine effect. The problem, once again, is that tinnitus is symptom - so it is like treating a cough, and a cough might be TB or terminal lung cancer or it might simply be a time-limited cold or allergy. We also need to differentiate those T sufferers who are young and likely have a treatable cause from those, like myself, who have age-related or trauma-induced bilateral tinnitus related to hearing loss and for whom there will be no 'cure'. However, there are effective management strategies.
      • Like Like x 2
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    29. Amelia

      Amelia Member

      Tinnitus Since:
      I'm currently taking flavanoids ... Do you have any links about these?

      (Note - I'm taking flavanoids for sinus issues not T)
    30. Marie

      Marie Guest

      I was wondering if anyone knows anything about the anesthetic than ents use to numb your eardrum with a myringotomy. I had a myringotomy a month ago and my ear immeditely started ringing right there in the exam room right after procedure. The drug is phenol. I believe it is some type of benzene. I read information that if it gets into your inner ear it damages the cochlea. I'm just wondering if this has happened to me. If you do a search on phenol used on the tympanic membrane there are about three different write ups about it. Would someone check into this for me as I want to make sure that I read everything right and understood it correctly. This ringing in the ear after having a myringotomy has happened to a few other people as I did a search. If my cochlea isn't damaged by this drug then why is my ear still ringing? I never had tinnitus before.

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