Top Treatments to Consider in the Early Days After Onset

@Juan - actually I had prednisolone not prednisone. My mistake!

Still no taper and completely different packaging. I know it will differ country-to-country.

The difference is interesting: The main difference between prednisone and prednisolone is that prednisone must be converted by liver enzymes to prednisolone before it can work. In people with severe liver disease, prednisolone is usually preferred.

Steph

 

Do the treatments listed apply only to acoustic trauma induced T or do they equally apply to T arising from an unknown cause?

 

Unfortunately, Lenire is only accepting "chronic" cases (I think it was a year after onset at the earliest). Their little intake questionnaire told me I had to use my hearing aids for a year before I was a candidate. Womp womp.

 

Can Prednisone still help 5 weeks out of an acoustic trauma?

I tried it in the beginning (just one 10 mg pill) and the side effects were tough on me (burning skin, nausea, restlessness) so I gave up. I thought how can I handle 40 mg of this when I can barely tolerate 10 mg? However, my tinnitus has worsened in the last week, likely with continued swelling in my ear.

I am wondering if I should give it another go as one last ditch attempt and to prevent this from worsening.

 

I am currently in my first week of Prednisone use. 60mg/day the first four days! I know how you feel CAgirl. Pretty wired right now, typing is more difficult than normal. Onset of tinnitus was September 1st, and thankfully I recognized what was going on and went to the ENT right away. Sleeping is difficult - not sure if it's the medication or the constant hiss.

Did you go in for more Prednisone? What were the results?

 

Same, neither have done anything. I did have one day that I felt a little better but it was just for part of the day - I wonder what it was that helped so much, probably not those meds, haha. I wonder what CBD oils work best

 

I'm in a very similar situation to everyone here. I had a very bad experience with earbuds and not noticing how bad it was, and then being told by a family member to try some high does aspirin (wow right?).

Unfortunately, everyone in my life would rather of coddled me than helped me including doctors.
I managed to get steroids but I think it was too little avail, only 4 days worth, I'm back on them for the last 2 weeks and to be honest, have only noticed it getting louder with some moments where it quiets at night briefly.

I'm also doing HBOT... but 2 weeks in. I've done a few sessions so far and have to say I've had no effect, it's possibly even gotten worse. There could be some delayed reaction but I'll keep you all in the loop. I also have been taking tons of supplements antioxidants but who knows right? I didn't get the good one, NAC in time... and asking doctors for help is pulling teeth.

The ENT was not helpful in regards to recommending anything but HBOT (I asked for steroid injections and he wasn't into it).

Trying to live with this, is really terrifying at my age, I'm still trying to get a family together. Even in a noisy environment is absolutely brutal, sleep doesn't exist. I don't see how I can work in an office like this.

I don't know what effect the steroids have had really, but I'm now tapering 3 weeks in. I might try one more large dose at the end to see if there's any reduction that day or not.
Pretty much out of options.

Benzos work for volume reduction, but yeah... they have their own big problems.

Any advice?

 

What benzo were you on and at what dose?

 

Start taking NAC and magnesium and bide your time. Protect your ears, and you could consider seeing another ENT and pushing for steroids if you want.

 

What's the timeframe for Dexamethasone? I got pain hyperacusis 5 weeks ago and am seeing an ENT. I want to try to push for a round window injection.

 

I'm not sure if there is clear efficacy but I've heard up to three months according to some sources. No idea if it would help for hyperacusis as it is usually studied with regard to hearing loss, and people append it to tinnitus as such.

 

I don't think Dexamethasone works 3 months after.

After being exposed to loud noise, ears develop a series of symptoms, pressure, muffled hearing, tinnitus, hyperacusis, etc etc... this rarely subsides (the acute phase of symptoms) after 2 months. It would be very rare. There is usually a horrible period of 10 days after noise exposure, then the other time mark is like 3 weeks. To have an acute phase of symptoms for 2 months means major hearing damage, with permanent hearing loss. And more than 2 months, I think it is very rare.

When symptoms go away (acute phase) usually whatever is left is your baseline hearing, or the real situation of your ears...

So having corticoids, including Dexamethasone, like 2 month after... I don't see it. I think even 3 weeks after is really really late...

 

Do you think that it's a good sign if tinnitus changes / increases in frequency and loudness while on Methylprednisolone?

Doctors here say that it's good, because it shows that the steroid does something.

This is not my personal issue, I'm just wondering.

 

Did yours spike while you were taking Prednisone? I just tried it and mine is through the roof.

 

Mine was ALWAYS better on Prednisone, but ALWAYS made me twice as bad coming off.

Permanently.

I'd do one course tops and live with what you get on the other side... and taper super duper slowly even if the course is just "2 weeks", like taper over another 2 weeks at least.

Ginkgo biloba and Magnesium are probably the best things to use early on... or any vasodilators.

 

Thanks so much for getting back. I think I might call it quits tomorrow. I'm not showing any good signs and don't want to see where I'll be in 8 days.

 

There are studies that suggest that getting your Glutathione status up before and/or quickly after an exposure can help prevent some of the oxidative stress damage. One study used NAC plus Glycine and other discussions recommend some of the cofactors in the synthesis process such as Magnesium, Selenium, B2, vitamin C, Lipoic Acid. In another study, correcting a B12 deficiency lowered tinnitus loudness scores in deficient subjects.

George

 

Noise conditioning, so listening to low levels of noise a lot actually helps hair cells resist oxidative stress, as those reduction enzymes get upregulated in mRNA expression. So that the next time it happens, they can deal with the higher levels of free radicals.

Of course, supplementing helps so long as it isn't toxic and can get into the nerve and hair cells via lipid solubility and mechanotransduction channels, respectively.

 

I noticed in your profile that you list Prednisone as a cause of tinnitus. I finished my first 5-day Prednisone course for hip pain and developed severe light sensitivity. Got my eyes checked, nothing found. That has faded by about 80%. A couple of weeks later a brief leaf blower exposure seemed to cause my tinnitus and hyperacusis or so I thought. Could this have been brought on by the steroids themselves?

George

 

No, I doubt it. It was probably the noise exposure.

Upon finishing the steroids I knew immediately something was very wrong. I had new noises in the morning on awakening (bilateral drones) and nothing sounded "crisp". The sounds got a bit better but now there's distortions, the drones have turned into... best description is just pure nonsense in both ears when I wake up in a silent room.

Could the steroids have "primed" you to get worse? I wouldn't doubt THAT given my experience with them. While on them if I got exposed to noise, that noise "stuck around" in my bad ear.