MDMA (a Component of Ecstacy) Potential for the Treatment of Tinnitus

Discussion in 'Research News' started by tomytl, Mar 9, 2014.

    1. Robb
      Question it

      Robb Member Benefactor

      Location:
      Germany
      Tinnitus Since:
      09/2013
      Interesting, this should encourage scientific research centered around this substance.
      There will come a lowering substance anytime soon as I notice after having eaten raw vegetables that my T lowers

      Add on: = ) Trials are partly finished so to read, wow that is quick!
       
    2. RaZaH
      Cheeky

      RaZaH Member Benefactor Hall of Fame

      Location:
      Reykjavík, Iceland
      Tinnitus Since:
      2012/04
      Cause of Tinnitus:
      Benzo + loud noise
      I went for it. Pure MDMA from a very good friend of mine. Did nearly one full trip dosage over a whole Sunday , just chilling. Only tiny amounts at a time and never really went over a slight buzz, what can I say , I was desperate.
      I felt a definite reduction during , day after was a bit bluesy but not bad in regards to T.

      Since then it has gotten much , much better.
      I have actually had days where I hardly noticed it, first time in two years !
      VERY probably a coincidence , in fact extremely probable.
      I also started drinking Turmeric Spice in water every day at the same time...not sure why ? :p
      T makes me try/do silly stuff !

      I also made a sound with crickets , notched and played ACRN on top of that for a couple months, maybe that helped?
      In any event it has gotten much better for me , lower 3.1 khz tone is pretty much gone.
      Still have that annoying bitcrushed 13-15 khz hi tone , but mostly when I wake up and go to sleep, days are pretty good , which is new for me. Its annoying me at the moment to be honest, but its bedtime.

      If MDMA was a CURE ....we would probably know by now.
      It was a great day though. :)
       
    3. jazz
      No Mood

      jazz Member Benefactor

      Location:
      US
      Tinnitus Since:
      8/2012
      Cause of Tinnitus:
      eardrum rupture from virus; barotrauma from ETD
      Well, I am happy for your reduction, though I never would try it.:) But perhaps doctors can formulate a version of it that would be acceptable for tinnitus sufferers.

      So please let us know how long it lasts.
       
    4. SoulStation
      No Mood

      SoulStation Member Ambassador

      Location:
      New York
      Tinnitus Since:
      2012
      Cause of Tinnitus:
      Noise / Possible Medication
      That's awesome. How are you feeling now? Do you think your 3.1k went away because of ACRN and notched pink noise? Or was it the MDMA?
       
    5. SoulStation
      No Mood

      SoulStation Member Ambassador

      Location:
      New York
      Tinnitus Since:
      2012
      Cause of Tinnitus:
      Noise / Possible Medication
      I highly highly doubt this would ever fly in the states . Too many raver kids would OD. It makes me sick cause it could actually help .
       
    6. Grace
      No Mood

      Grace Member

      Tinnitus Since:
      11/14/2013
      I couldnt imagine them prescribing mdma ecstasy in that type of form.. They would have to figure out what parts of the mdma or something that helps T and then make another
      Form of it without it making you high, so no one else would get anything out of it unless you have T.
       
    7. RaZaH
      Cheeky

      RaZaH Member Benefactor Hall of Fame

      Location:
      Reykjavík, Iceland
      Tinnitus Since:
      2012/04
      Cause of Tinnitus:
      Benzo + loud noise
      @SoulStation
      I would have to say that I think it is more likely that the notched cricket sounds and ACRN was what helped me the most. I base that on the fact that it gives me instant relief listening to it and it seems to work for some people.
      However , fact is ...the reduction happened a couple of days after taking the MDMA .
      Anybody's guess really.

      I do not want to be responsible for anyone doing illegal drugs , but want to be honest.
      The T problem is far from gone and still bothers me but again, getting days where I dont notice it and that is a huge improvement for me.

      I might try it again ?

      Btw: I get super "high" from taking a Benzo , so why not MDMA ?
       
    8. earsnothappy

      earsnothappy Member

      Tinnitus Since:
      May 2014
    9. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      donate?? I think american government should give money flat on their hands and knees ... my god American government is biggest criminal on the planet.

      @RaZaH

      I think you are completely right, MDMA is superiour to benzos in all respects! It makes you open, concious, loving, insightful ... Sasha Shulgin, the inventor of MDMA recently died at the age of 88 and he was happy and clear, though suffering in his later years.. he took around 4000 substances in his live. Most of which he designed himself.

      http://www.cbsnews.com/news/alexander-shulgin-godfather-of-ecstasy-dies-at-88/

      I`m going to investigate ketamine with the hope to have some benefit for T. Also they are doing test for depression and I do think I have some feats of depression. I don`t call it like that and would never take any overcounter drugs for it.. but if you compare how I was 5 years ago and now it is very different. Used to be outgoing and alive, now mainly tired and just silently going about life ... or is this maybe what they call growing up? :) ... no but my T has left his imprint on me in a negative way.
       
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    10. earsnothappy

      earsnothappy Member

      Tinnitus Since:
      May 2014
      @nills

      I'm sure you're aware that AM-101 is Esketamine, which is a form of Ketamine. My understanding is it's twice as powerful with 50% the half life as Ketamine.
       
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    11. SoulStation
      No Mood

      SoulStation Member Ambassador

      Location:
      New York
      Tinnitus Since:
      2012
      Cause of Tinnitus:
      Noise / Possible Medication
      I personally don't think I'm going to try this cause I'm on a daily benzo/ an anti depressant and prone to depression already and feel like its too dangerous (also don't have a source for it).
      Though you never know. I'm pretty desperate for any relief most days. Please keep us updated ! And so glad to hear of some good days for you.
       
    12. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      @earsnothappy true, it is esketamine . Thanks for pointing it out.

      I think one aspect of the benefit of MDMA is that it produces a happy feel, it boosts serotonin, maybe that has something to do with the brain being able to lock out T sounds. Also Ketamine produces happy feelings, though it is a lot stronger and can make you trip out pretty hard, it slows down and speeds up perception of time, minutes seems like seconds, seconds can become hours. i will start little doses and than judge if it is worth to continue the experiments with higher doses.

      I found interested thread on another forum about MDMA and tinnitus. Here people also say the t goes away on the peak of the MDMA experience.

      http://www.bluelight.org/vb/threads/131928-Tinnitus-and-MDMA

      @SoulStation I don`t know your history age and character, but benzo`s and antidepressants cover up your feleings and emotions. It is ok to feel sad sometimes... we live in a world that projects the perfect body, the perfect job the perfect wife and to be happy always... it is a scam don`t fall for it. I would discourage 95 percent of poeple taking pills to take it. the other 5 shouldn`t take them either but would cause harm to themselves if they wouldn`t. Drugs like MDMA or Ketamine do not cover up the feelings. But they can give insights in your life, they open up conciousness instead of muffin it up. You don`t take it everyday. you do it once every so often en make the experience as a psychotheraputic session where you prone into your self and life to see what created certian feelings and situations. Not trying to talk you into it, just spreading counter information to the world filled with government fueled lies that only keep us as sheep in their system. I would take an illigal drug any time over a legal one cause... why do you think it is illigal? cause it harms you? sooooo many drugs bring harm, only the ones that empower you are illegal... lsd, mdma, ayahuasca, ibogaine, 2cb, mushrooms and so on ...
       
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    13. RaZaH
      Cheeky

      RaZaH Member Benefactor Hall of Fame

      Location:
      Reykjavík, Iceland
      Tinnitus Since:
      2012/04
      Cause of Tinnitus:
      Benzo + loud noise
    14. john2012

      john2012 Member

      Location:
      Germany
      Tinnitus Since:
      2012
      @nills great post
      i'd love to get my partner some high-cbd, low-thc cannabis
       
    15. Strictlyt

      Strictlyt Member

      Tinnitus Since:
      01/2000
      This is interesting but as someone who took a fair amount of MDMA in my early 20s I can't say my T was ever cured. While out partying, I don't think I ever really noticed the T but that is probably because of the noisy environments.

      I know for a fact that alcohol makes my T worse but I never notice if I am having a drink with friends or family because my mind is fully focused away from the T. Maybe MDMA is similar to this.

      I can imagine MDMA being useful to distract the mind from listening to the T however. Will be interesting to see the final results.
       
    16. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      I took the mdma at home with my brothers and we just talked with music in the background, I focused on the T but could not find it ... something happens during that high that blocks it. But it does come back the next day or even late at night after the high wears off.
       
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    17. Grace
      No Mood

      Grace Member

      Tinnitus Since:
      11/14/2013
      Maybe they could use mdma or whatever in it as a mood stabilizer since it makes you happy and carefree and make you forget bout your T.. Like a drug that induces habutation or something and maybe it will just cure/treat somes T fully.
       
    18. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      Another invention of Sasha Shulgin is DIPT, related to sound and Tinnitus in it`s effect.

      DIPT
      The campanologist’s friend – or foe. This tryptamine – a mushroom-like drug – makes all sounds appear to drop by an octave or so, and makes many instruments sound like a clanging bell. But it offers a fascinating insight into the way humans process sound, and may one day help in the study of tinnitus, which it can temporarily cause.

      http://www.mixmag.net/music/the-blo...r-shulgin-designed-synthesised--and-then-took
       
    19. yonkapin

      yonkapin Member Benefactor

      Location:
      Melbourne, Australia
      Tinnitus Since:
      March 2012
      Glad you had a good time! :D

      What sort of doses were you doing? If you don't mind me asking that is.

      Doing small doses over a whole day isn't the ideal way to do MDMA. Usually you want to start with a dose of 100 to 120mg (depending on your weight and tolerance) and then follow up with that dose with something like 80 to 100mg (less than the first dose) if you want to continue your roll. People in reality tend to go overboard on dosing the stuff, as expected, but that's a rough dosing guide that balances having a good time and being able to recovery from the roll faster.

      When you hit the peak of your roll, you will definitely feel more than a slight buzz - you will be very euphoric and basically everything will be awesome, this is when the ego breaks down a bit and you really start to open up emotionally and have some fun.

      The reason why I mention that doing small doses over a whole day isn't ideal is that usually once your brain begins to release serotonin, the ability for the brain to continue doing so over that many hours diminishes as time continues, you hit a wall basically. So usually it's a good idea to start off strong and get things over within 3 to 6 hours.

      Also, it's always important to supplement before and after your rolls with stuff like vitamin C, magnesium, 5-htp and other anti-oxidants. Have a look around online (if you haven't already), there's some very specific guides out there that recommend various supplements to aid in recovery after an MDMA session, reddit and bluelight are great resources for this sort of information. The main 3 I mentioned have been very useful for me when it comes to recovery after a session.

      One other important thing, if you choose to try it again:

      I would suggest planning to do it with someone (or a group of friends) that you think you might be comfortable talking about your tinnitus with. I haven't done this specifically for tinnitus myself, but I've done this with other issues I was having and found that being on MDMA, with a group of close friends and being able to talk about the things that were troubling me, whether it was some sort of childhood trauma or issue that was bugging me, helped me tremendously! I was able to look at the issues that were bothering me in a truly objective manner that really wasn't ever possible in my usual state of consciousness, and then I was able to talk about this stuff openly with people I respect and have close bonds with. This process really helped me move forward with some stuff that had been troubling me for years.

      This is where I see the main benefit of using MDMA in the treatment of tinnitus. While I do experience temporary reductions in my tinnitus after a session, I think the main use of the drug will be to aid in the process of acceptance and habituation of tinnitus. Sounds hokey but it's what I think will probably be the main benefit from using it with tinntius.

      Quick edit: Just thought I'd point out to anyone reading this that I'm not condoning or encouraging anyone to go out and hunt down some MDMA to try. You really need to know what you're getting yourself into and what specifically to look out for, there are way too many greedy dealers who will do all sorts of mischief to make a quick buck, whether it's cutting product or using imitation research chemicals that can be potentially dangerous. Safety first.
       
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    20. benryu
      Anime

      benryu Member Benefactor

      Location:
      Montreal
      Tinnitus Since:
      12/2008
      Hey I have been on plenty of forums/ reddit / chat and I came across so many people who had long term T. improvement after taking Etc once.
      I am considering trying on myself in the very safe manner, I am chatting with a super close friend who is a pharmacist and is willing to help me in the quest of making a clean pill for a medicinal use.
      It's not legal, we are both taking risk, but I think if I can bring another positive testimony it will benefit the T. community, and as a university researcher I will be able to share my story with the right people.
      The process might take a few months, but I 'll keep you posted.
       
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    21. RaZaH
      Cheeky

      RaZaH Member Benefactor Hall of Fame

      Location:
      Reykjavík, Iceland
      Tinnitus Since:
      2012/04
      Cause of Tinnitus:
      Benzo + loud noise
      Yeah , I am going to try this again. I feel like I got a few good weeks from this at least.
      At least I think so ...its super hard to pinpoint any correlations with this T thing.
       
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    22. Bambi

      Bambi Member

      Location:
      Norway
      Tinnitus Since:
      08/2009
      Cause of Tinnitus:
      Unknown
      Hello,

      I don´t have the energy to read all that´s been posted on this subject, so hope someone can answer a few questions regarding this. Yesterday I read an article saying they hopefully could start up some trials on tinnitus afflicted and MDMA. This because there were a lot of tinnitus sufferers who reported their tinnitus going away after taking MDMA.

      Have anyone tried? Or heard about such a trial?

      And, do anyone know; would it be enough with one dosage, or would you have to keep taking it? I don´t see that as a viable option...

      Thank you :)
       
    23. newfie
      Inspired

      newfie Member

      Location:
      Canada
      Tinnitus Since:
      10/2007
      Cause of Tinnitus:
      Acoustic trauma (gun)
      Otonomy's OTO-311 therapy in the pipeline will be using an NMDA receptor antagonist.; Gacyclidine.

       
    24. JeffDamsko

      JeffDamsko Member

      Tinnitus Since:
      2010
      Did mdma twice in the last month. My t was definitely gone during the high. Didn't come back till next day dinner time but just got back to baseline both times.
      First time I was wearing hearing aids with noise generators and my annoyance to the t came back with it.
      I've stopped wearing them and I do feel less annoyed by it at the moment, let's see..........
       
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    25. Viking
      No Mood

      Viking Member Benefactor

      Location:
      Italia
      NMDA receptors...a target for tinnitus treatment.... MDMA and Special K: the most powerful releaser of serotonin (one of the most important neurotransmitter) in the brain to the centers of "feeling good". One day maybe we will find that the cure for tinnitus is often right where tinnitus is generated. at the disco:rockingbanana::rockingbanana::rockingbanana:
       
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    26. 1MW
      No Mood

      1MW Member

      Tinnitus Since:
      2008 but cured and relapsed from benzos
      Cause of Tinnitus:
      ssnhl/benzos/unknown
      One of good otoneurologists told me a story about one that had T and he taken
      some ototoxic antibiotic T stopped for some time 2-3 weeks and her hearing become worse.
      From 1000 persons that take this antibiotic 999 of them loose their hearing and develop T.
      1 in 1000 loose more hearing but T stops for some weeks.
      In rules there are exceptions confirm the rules.
      So ndma is something from this. 999 in 1000 bad 1 in 1000 good.

      Also read that someone with many years of T suddenly got stroke and T disappeared with stroke.
      He has not loose any hearing only T disappeared. But this was 1 in millions.
       
    27. Shiro

      Shiro Member

      Hello, what do you mean by stroke ?
       
    28. sergerold

      sergerold Member

      Tinnitus Since:
      11/11/14
      The risks of MDMA are seriously overrated.
       
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    29. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      not at all 1MW ... from the few people that shared their MDMA experiences here almost all had a relief in T ... Mine too vanished completely during the high. But came back next day. But it did give a boost in general well being and trust in life. I would do a MDMA / Ketamine treatment over Benzos ANY time! (never ever took a benzo in my life) the relief from these molecules are longer lasting, they are safer, have better effects on ones emotional well being and general understanding of life and they are less addictive .... truly the whole world is being conned and lied to by the FDA!
       
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    30. earsnothappy

      earsnothappy Member

      Tinnitus Since:
      May 2014

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