Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

Discussion in 'Research News' started by David S, Mar 1, 2022.

    1. David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Quite amazing results. What are your thoughts?

      Integrative Treatment for Tinnitus Combining Repeated Facial and Auriculotemporal Nerve Blocks With Stimulation of Auditory and Non-auditory Nerves
       
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    2. Ben Johnson

      Ben Johnson Member Benefactor

      Location:
      Georgia, USA
      Tinnitus Since:
      01/2022
      Cause of Tinnitus:
      Cervicogenic headaches, Anxiety, OCD, Zoloft
      If this is accurate, why isn't it being widely circulated and duplicated all over the planet? Frustrating.

      Thanks for sharing.
       
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    3. DimLeb

      DimLeb Member

      Tinnitus Since:
      03/2021
      Cause of Tinnitus:
      Idiopathic Cochleopathy or Maybe Loud Music
      This is quite big! I can't understand from the article though, if they found it works on most tinnitus vs. only on some subset.
       
    4. grayfox00

      grayfox00 Member Benefactor

      Location:
      Poland
      Tinnitus Since:
      03/2021
      Cause of Tinnitus:
      Unknown
      No control (placebo) group...
       
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    5. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Lidocaine is well known to suppress tinnitus temporarily via blood infusions. This is a much more direct approach. Also electric stimulation aimed at the cochlea suppress tinnitus. It is much easier to get close to any of the binding nerves.

      I like this approach a lot.
       
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    6. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Yes I know, but double blinded. Phase 1/2, Phase 2, Phase 3 trials will take 5-10 years.

      I feel we need more hope for the short term.
       
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    7. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Anyone here from South Korea here that can look into this? The procedure seems quite safe. All known and well tolerated drugs.
       
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    8. grayfox00

      grayfox00 Member Benefactor

      Location:
      Poland
      Tinnitus Since:
      03/2021
      Cause of Tinnitus:
      Unknown
      Even without a control group, the effects are quite impressive. I doubt that someone could report such big improvement due to the placebo effect.

      Does it need to go through a series of clinical trials? If I understand correctly, this is a combination of methods we already have.
       
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    9. DocTors_94
      In pain

      DocTors_94 Member Benefactor

      Location:
      Spain
      Tinnitus Since:
      11/2021
      Cause of Tinnitus:
      Loud noise/ Covid? / Benzos / Ototoxicity
      I very much agree with @grayfox00. The results are SPECTACULAR to say the least. It's just impossible to get VAS score down 7 points (from severe to mild) in so many patients by placebo effect... I would fly to South Korea right now if this could be done by compassion.
       
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    10. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Yes, everything is very well known. The new approach is that you guide the needle very precise to get close to the nerve that you want to block or stimulate. You guide with low radiation CT (similar as pictures that you take at the dentist) or with ultrasonic.
       
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    11. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor Hall of Fame

      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      Nonnatural energy source
      Looks like the study was just published, 02/2022.
       
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    12. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      You got to start somewhere. Also this is a quite expensive treatment. Every injection would be somewhere around $500-1000 per occasion. Chronic tinnitus might need 15 or more treatments. Need to be done by very skilled doctors to not hurt the nerves.

      Not a pill or a device the big pharma can earn any money out of.
       
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    13. Freerunner

      Freerunner Member

      Tinnitus Since:
      10/2021
      Cause of Tinnitus:
      Caloric test
      Wow, even the effects were still ongoing after 1 year. Well, is this procedure to be used in other countries as well? What do you think? If it is indeed so successful, maybe it will be implemented at ENT practices and for once they will be useful for us.
       
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    14. Gb3

      Gb3 Member

      Tinnitus Since:
      12/19
      Cause of Tinnitus:
      Sshl
      Don’t any of you people have health insurance?
       
    15. DimLeb

      DimLeb Member

      Tinnitus Since:
      03/2021
      Cause of Tinnitus:
      Idiopathic Cochleopathy or Maybe Loud Music
      Oh, I see. It still looks like a lot more viable treatment than stem cells, for example, which cost just about the same. I believe it's very promising that these news keep popping up and something is finally moving in the right direction!
       
    16. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Very much agree. No way a placebo effect cloud knock out my chronic tinnitus.
       
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    17. AUTHOR
      AUTHOR
      David S

      David S Member Benefactor Ambassador

      Tinnitus Since:
      10/2013
      Yes I do, but cost would not be a big concern to me if it really works. Just a small effect on what it takes to mask my tinnitus would mean the world to me.
       
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    18. MartinPihl

      MartinPihl Member Benefactor

      Location:
      Denmark
      Tinnitus Since:
      2021
      Cause of Tinnitus:
      Unkown
      Nice - Thank you for posting this. Stuff (and posts) like these are the reason I can keep going!
       
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    19. Ben Johnson

      Ben Johnson Member Benefactor

      Location:
      Georgia, USA
      Tinnitus Since:
      01/2022
      Cause of Tinnitus:
      Cervicogenic headaches, Anxiety, OCD, Zoloft
      Are there people on Tinnitus Talk who can push this study to the front and center of the medical community?

      The study sounds very hopeful and I would hate to see red tape and regulations drag it to a snail's pace.
       
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    20. Gb3

      Gb3 Member

      Tinnitus Since:
      12/19
      Cause of Tinnitus:
      Sshl
      Correct me if I’m wrong. All of these drugs are approved so there are no trials to conduct. How does a potential treatment become a standard of care?

      Example: Steroids are given to people with hearing loss but from my understanding there is no evidence that they help at all but that is the standard of care.
       
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    21. Ctjbush
      Alienated

      Ctjbush Member

      Tinnitus Since:
      August 2018
      Cause of Tinnitus:
      Probably loud music, old age
      Sounds good. How can we get this treatment?
       
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    22. AnthonyMcDonald
      Confused

      AnthonyMcDonald Member

      Location:
      Russia
      Tinnitus Since:
      06/2021
      Cause of Tinnitus:
      Noise induced
      Right now? Fly to Korea for a few weeks.
       
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    23. Brian Newman

      Brian Newman Member

      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Shooting/loud noise
      Nice. I wonder how they will move forward with the treatment. I’m guessing more people to test it on. We will find out soon since it’s a new article.
       
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    24. InNeedOfHelp

      InNeedOfHelp Member

      Tinnitus Since:
      08/2021
      Cause of Tinnitus:
      MRI Scan
      This actually seems like a Phase 1/2 combined study already. Phase 1 is for safety Phase 2 is for efficiency. It is clearly not but i doubt this has to run through a Phase 1/2/3.

      Placebo seems quite risky since this is quite a risky procedure. You don't want to end up giving someone permanent facial damage by applying placebo needling in their face..
       
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    25. Freerunner

      Freerunner Member

      Tinnitus Since:
      10/2021
      Cause of Tinnitus:
      Caloric test
      I am not sure but yesterday I emailed one of the researchers who was given as a point of contact. I asked if they are implementing this practice in their clinics and what would be the cost. I am currently awaiting for a response.
       
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    26. Reed19
      No Mood

      Reed19 Member

      Tinnitus Since:
      At least 4 years ago or my whole life
      Cause of Tinnitus:
      Unknown, ear infection, head trauma, music, drugs, badsleep?
      This sounds too good to be true. Why are we not doing this right now?
       
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    27. Padraigh Griffin

      Padraigh Griffin Member Podcast Patron Benefactor

      Tinnitus Since:
      05/2020
      Cause of Tinnitus:
      Unknown/Stress
      Was I correct in seeing ‘somatic tinnitus’ as an exclusion criteria?

      Also, as it is a new surgical approach, not a drug or medical device, I presume clinical trials are not necessary?

      For those of us in Europe/UK it is interesting to see Dr. Will Sedley as a peer reviewer.

      The results are amazing.
       
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    28. ajc

      ajc Member

      Tinnitus Since:
      11/2002; spike 2009; worse 2017-18
      Cause of Tinnitus:
      Loud music - noise damage
      Inclusion criteria included:

      6. subjective tinnitus regardless of whether accompanied by sensorineural hearing loss, objective or somatic tinnitus, or unidentified brain diseases.

      Exclusion criteria included:

      5. purely objective or somatic tinnitus.

      So nothing to worry about. Most people with subjective tinnitus have some somatic tinnitus. And those people are eligible. I'm not sure what "purely somatic tinnitus" is, maybe it means there's like a tumor or some actual identifiable somatic issue causing the tinnitus.
       
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    29. InNeedOfHelp

      InNeedOfHelp Member

      Tinnitus Since:
      08/2021
      Cause of Tinnitus:
      MRI Scan
      Before we all get our hopes up, this paper was written by a private clinic's owner (and family members I assume, based on the last names.) I didn't come across any other publications under these names.

      It seems they may have a large financial benefit from patients coming to their clinic for this treatment.

      It's not university/pharmaceutical company research.

      This would not be the first time hopeful results might be debunked later on...
       
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    30. Padraigh Griffin

      Padraigh Griffin Member Podcast Patron Benefactor

      Tinnitus Since:
      05/2020
      Cause of Tinnitus:
      Unknown/Stress
      Thanks. The inclusion and exclusion is confusing. I think it might refer to muscular tinnitus, something I recently had surgery for, but I have ordinary tinnitus too.

      Either way, hopefully this procedure is rolled out globally as soon as practically possible!

      Pity more controlled trials are needed. Hopefully they might be global though.
       
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