University of Minnesota Tinnitus Research with Acoustic and Body Stimulation

Discussion in 'Research News' started by kelpiemsp, Apr 2, 2018.

    1. hans799
      Mellow

      hans799 Member Benefactor Hall of Fame

      Location:
      Hungary
      Tinnitus Since:
      Born with it
      Cause of Tinnitus:
      Worsened Dec 2016 by headphones
      I mentioned neural networks in the sense that Dr Shore models the brain parts responsible for tinnitus as a feedforward neural network, and uses this model to arrive at the correct timings. So to replicate the timings we'd need to come up with a similar model, which would require serious neural networks expertise.

      But in this case we're talking about a literal network of living neurons, not neural networks in the machine learning sense (although that would surely be cool).

      For example, see this study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566901/
       
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    2. GregCA
      Jaded

      GregCA Member Benefactor Hall of Fame

      Tinnitus Since:
      03/2016
      Cause of Tinnitus:
      Otosclerosis
      Ah ok, thanks for clarifying! I thought you meant in the machine learning sense, and that triggered my curiosity!
       
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    3. Paulmanlike

      Paulmanlike Member Benefactor Hall of Fame

      Tinnitus Since:
      2008
      Cause of Tinnitus:
      Noise
      Just let the woman do it for you, don’t build machines, leave it to the expert Susan Shore.
       
      • Agree Agree x 3
    4. SuntoryTime
      Caffeine

      SuntoryTime Member

      That's an educated guess. Large scale Phase III trials tend to take years, realistically 3 to 5. The Shore device will arrive before FTX's more complex technology because it has been in the clinical trial pipeline longer. I'd be delighted to be wrong about this and have both technologies available sooner. But I guess I can wait a little longer. I am now surviving on sheer force of will.
       
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    5. MadsWithT
      No Mood

      MadsWithT Member Podcast Patron Benefactor

      Location:
      Norway
      Tinnitus Since:
      1997
      Cause of Tinnitus:
      See bio
      By evaluating the various possible treatments from a layman’s perspective. Hence, my opinion is subjective. I’ll certainly respect other opinions but I won’t go into a long chain of arguments on the merits of the range of different venues being explored in order to cure tinnitus. I understand that you are in favor of some drug. If that drug turns out to cure the ailment, I would be very happy. However this thread concerns the bi-Modal avenue. I would be very happy if that works. That’s how I figure things.
       
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    6. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      I highly recommend you look into this some drug.
       
    7. MadsWithT
      No Mood

      MadsWithT Member Podcast Patron Benefactor

      Location:
      Norway
      Tinnitus Since:
      1997
      Cause of Tinnitus:
      See bio
      Sure.
       
    8. Paulmanlike

      Paulmanlike Member Benefactor Hall of Fame

      Tinnitus Since:
      2008
      Cause of Tinnitus:
      Noise
      • Helpful Helpful x 1
    9. Rafahyperacusis

      Rafahyperacusis Member

      Location:
      Spain, Valencia
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      noise exposure
      Do you think this is gonna work for people who has H too @kelpiemsp ?
       
      • Good Question Good Question x 2
    10. PDodge
      Cowboy

      PDodge Member Benefactor

      Location:
      Woods of Alberta
      Tinnitus Since:
      01/2017
      Cause of Tinnitus:
      Bear ate my Cochlea
      When is this trial supposed to end?
       
      • Good Question Good Question x 2
    11. Don Tinny

      Don Tinny Member

      Location:
      Argentina
      Tinnitus Since:
      2017 (worsening)
      Cause of Tinnitus:
      Loud concert with ear plugs
      Perhaps it was already asked before. Are Minnesota's trials for somatic tinnitus? or are they more similar to Neuromod's?
       
      • Good Question Good Question x 1
    12. spedgas
      Scared

      spedgas Member Benefactor

      Tinnitus Since:
      09/2018
      Cause of Tinnitus:
      Unknown
      I have no idea where they are in the process. Does anybody have any idea where the University of Minnesota is in the process and what their expected end date is?

      I’m also wondering if there will be any issues with Hubert Lim being poached by Neuromod. How involved was he at the University of Minnesota?
       
      • Good Question Good Question x 3
    13. AUTHOR
      AUTHOR
      kelpiemsp
      Swamped

      kelpiemsp Member Benefactor Hall of Fame Advocate

      Tinnitus Since:
      birth/ recent spike 2/2018
      Cause of Tinnitus:
      Born with ETD, several acoustic traumas, most recently ETD
      Just last night my wife said "wow your tinnitus must be better" I said "why's that?" She replied...well a balloon popped and you didn't run out of the room. I paused and was like...huh. So yes, it really does. I was sensitive to all sound above 60 db for quite some time.

      All signal timing is the same, it IS using a somatic pathway. Will have to wait for more information.

      December 31st, 2018

      I'm super curious about this. I think Lim is still running this trial. If I had to guess, he will be in both spaces. It makes sense from Neuromods point of view. Neuromod probably brought on Lim to acquire IP from the trial at the UofM.
       
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    14. parsky

      parsky Member

      Tinnitus Since:
      8/1/17
      Cause of Tinnitus:
      Unknown
      This is pretty cool. Hopefully the only side effect is increased happiness!
       
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    15. PDodge
      Cowboy

      PDodge Member Benefactor

      Location:
      Woods of Alberta
      Tinnitus Since:
      01/2017
      Cause of Tinnitus:
      Bear ate my Cochlea
    16. Johan_L

      Johan_L Member

      Location:
      Sweden
      Tinnitus Since:
      05/2015
      Cause of Tinnitus:
      Noise induced
      So... Your sensitivity to sound improved? Did/do you have H?

      Also.. December 31st was yesterday! Is the trial over now?
       
      • Good Question Good Question x 1
    17. duder12

      duder12 Member

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      High Frequency Hearing Loss
      I finished the trial but we have not gotten a final report that I am aware of. I have tinnitus/high frequency hearing loss in both ears and can modulate it with my jaw.

      My personal opinion is that it did nothing for me.

      My tinnitus was fairly new before my treatment though so I was getting used to it as the trial went on. I'm going to try and see if it gets worse now that the trial is done but I'm guessing it will be the same.
       
      • Informative Informative x 5
    18. MadsWithT
      No Mood

      MadsWithT Member Podcast Patron Benefactor

      Location:
      Norway
      Tinnitus Since:
      1997
      Cause of Tinnitus:
      See bio
      Say, you write that Meniere's decease is your cause of tinnitus. I mean to recall that that particular cause was a exclusion point form these trials? Or am I wrong?
       
    19. Don Tinny

      Don Tinny Member

      Location:
      Argentina
      Tinnitus Since:
      2017 (worsening)
      Cause of Tinnitus:
      Loud concert with ear plugs
      It sounds pretty hopeless. It is assumed that these devices (Minnesota and Michigan) are more effective than the MuteButton. :unsure:
       
      • Informative Informative x 1
    20. Bill_
      Balanced

      Bill_ Member

      Location:
      Germany
      Tinnitus Since:
      04/1998
      Cause of Tinnitus:
      1. loud Concert | 2. loud club | 3. tympanometry
      Considering that his tinnitus was caused by Mèniere's I wouldn’t throw my hopes out of the window just yet. Mèniere's might very well be a rather „special“ case.
       
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    21. Manny
      In pain

      Manny Member Podcast Patron Benefactor Hall of Fame

      Location:
      United States
      Tinnitus Since:
      1/2018
      Cause of Tinnitus:
      central gain << NIHL
      @kelpiemsp per your status you now have silence?? Wow!! May I please hear more?
       
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    22. hans799
      Mellow

      hans799 Member Benefactor Hall of Fame

      Location:
      Hungary
      Tinnitus Since:
      Born with it
      Cause of Tinnitus:
      Worsened Dec 2016 by headphones
      Wow! Looking forward to his reply :)

      T is behaving badly this evening. A dose of hope is nice.
       
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    23. Jack Straw
      Balanced

      Jack Straw Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Location:
      US
      Tinnitus Since:
      1990s
      Cause of Tinnitus:
      Infection, Acoustic Trauma
      upload_2019-1-9_13-54-32.jpeg
       
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    24. Jack Straw
      Balanced

      Jack Straw Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Location:
      US
      Tinnitus Since:
      1990s
      Cause of Tinnitus:
      Infection, Acoustic Trauma
      Start the hype train for biomodal stimulation?
       
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    25. Manny
      In pain

      Manny Member Podcast Patron Benefactor Hall of Fame

      Location:
      United States
      Tinnitus Since:
      1/2018
      Cause of Tinnitus:
      central gain << NIHL
      How can I rate a post "hug" and "good question" at the same time?
       
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    26. hans799
      Mellow

      hans799 Member Benefactor Hall of Fame

      Location:
      Hungary
      Tinnitus Since:
      Born with it
      Cause of Tinnitus:
      Worsened Dec 2016 by headphones
      Well, with @Clare B and @kelpiemsp both reporting silence from various bimodal treatments, plus an encouraging study from Dr Shore last January and even more encouraging preliminary results from Neuromod in the Q&A, the hype train is starting to move I think
       
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    27. Jack Straw
      Balanced

      Jack Straw Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Location:
      US
      Tinnitus Since:
      1990s
      Cause of Tinnitus:
      Infection, Acoustic Trauma
      Haha looks like we’ll be getting drinks sooner than I thought!

      I know this isn’t neuromod but it proves for a FACT that this type of technology works from a legit forum member. Great news today everyone!
       
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    28. Jack Straw
      Balanced

      Jack Straw Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Location:
      US
      Tinnitus Since:
      1990s
      Cause of Tinnitus:
      Infection, Acoustic Trauma
      upload_2019-1-9_14-5-58.jpeg
       
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    29. hans799
      Mellow

      hans799 Member Benefactor Hall of Fame

      Location:
      Hungary
      Tinnitus Since:
      Born with it
      Cause of Tinnitus:
      Worsened Dec 2016 by headphones
      If you look, it was actually @kelpiemsp who started this thread and brought Minnesota to our attention. He pulled himself up by his own bootstraps.
       
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    30. EDDTEKK

      EDDTEKK Member

      Location:
      Germany
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Acoustic Trauma
      Why he doesn’t share such experience in this thread :( we need some hope and success stories.
       
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