Hough Ear Institute's Hair Cell Regeneration Project

Hough Ear Institute: Bringing Back Silence

 

Thanks for sharing. I hope that this project can get further off the ground this summer so that we can start seeing more progress.

 

How incredible would this be. Eat a pill, see ya later tinnitus.

 

They say they need to raise $125K to move this forward to Phase II? That's a drop in the bucket in the bigger scheme of things and should be no problem to raise instantly if their drug held any promise and they had any confidence in it at all.

Something doesn't pass the sniff test in my view.

 

Duh... Tell 'em: "Sell the pill to Otonomy, Audion or Frequency Therapeutics for $125K dollars. They might use the ideas behind it or find them useful."

 

Freaking Bezos spending a half billion dollars for a rocket carnival ride to kinda in space, while people need help. All that money could have been used for good instead of some billionaire getting his rocks off.

 

The hearing loss pill consists of NHP-07 and NAC. NHP-07 has already been tested for safety in previous trials, NAC is over the counter so why do we need so many years of trials for NHPN-1010? This system is rotten.

 

It is a cruel world in which one lives, man is insignificant in it.

 

Exactly, all these billionaires doing pointless shit where all they have to do is donate a million and we can all get our lives back.

If any of these guys were smart, they'd purchase a part of the company or invest.

We all know if you were a part of the company that made a tinnitus or hearing loss cure, you would make an insane amount of money while helping people.

 

The problem is, they're already stupidly, unfathomably rich beyond any normal comprehension from the investments they've made in their own companies. So rich that they can bootstrap the majority of a private space program for at least a decade!

So, why bother investing chump change into a hearing loss drug that may/may not pay off for years, and when it does, is like a rounding error in their bank account?

Also, Space is super sexy and attention/imagination grabbing while restoring hearing is not. Unfortunately.

 

See so this is the same issue that Hough Ear Institute has had throughout their research processes. Pretty positive that the theory is that no matter how good their work might be, they have failed to clearly communicate components of their funding/fundraising methods. This has left people somewhat confused and concerned with where/what the money would be utilised on.

To date Hough Ear Institute has not adequately explained the following:

1. Why donations for hearing loss cannot be used towards their tinnitus medicine when it is inevitably also treating hearing loss.

2. Which parties are going to benefit from the sales of this medicine.

3. The reason(s) why they need funding from the public and donors towards development of this treatment when it appears on face value that there's two pharma companies who own rights to this treatment if it is successful.

4. What they need the current gap in their funding for.

5. What potentially will be given to donors in exchange for donating.

Simply until these (and possibly other) matters are answered, a lot of people are still going to have queries and concerns about what they are doing as an entity. Essentially the biggest issue with Hough Ear Institute has been the lack of communication from them about these type of key issues and this has been further compounded by the fact that when pressed or queried on such things they seem to either avoid answering them or provide vague answers.

The end result is that Hough Ear Institute presently reminds me of a car for sale which won't start and the owner can't tell you why. Fix the problem or give answers and it is almost certain that people will be more willing to entertain what is actually being offered.

 

True, you're right man We gotta raise the money, there has to be a few millionaires suffering from tinnitus and hyperacusis. There has to be.

 

No man! What we have to do, is invest in, and create a pair of, SPACE HEADPHONES!! that these rich dudes can wear and use on a daily basis... then we'll see the funding rolling in...

 

Lmaooooooo Ikr.

 

To elucidate the spirit of this post further, Elon Musk wants maximum attention and engineering credit for his successes. He probably cares more about that than money, although, they are deeply interconnected.

 

I guess you're right, but while I'm with people and their fascination for space I think hearing and especially music that "gets to your mind" is one of the most awesome experiences one can have as a human being – I think many (most?) people agree on that. So "fixing" or improving this is something that means the world (and space?) to people.

My tears ran when I listened to a couple of songs I like post high frequency hearing-loss loss and accompanying tinnitus – not the same nuance in the high frequencies.

Fixing this and hopefully in the same time getting rid of tinnitus associated with the hearing- should be concidered sexy indeed!

 

I was hoping the music industry would get involved at a certain point. They seem to go hand and hand...

 

This is something I've wondered too. Soooo many artists have tinnitus, yet very few speak out about it. And when they do, it's usually because it's too severe for them to continue making music.

I'm also confused as to how more people in the music industry don't have hyperacusis? Especially since people continue to wear headphones, go to shows, etc., after developing tinnitus. It makes me feel crazy because I've done nothing but protect my ears, avoid headphones, listen on monitors at safe volumes, and my tinnitus is getting worse.

 

One of life's greatest mysteries.

 

They embrace the suck until they can't. I read of a guy who now has hearing distortion finally and he can't really do crowds anymore.

 

Everyone's hearing is different and will degrade at different rates. Bad genes and a few rock concerts and here I am... Some people with good genes can hit thousands of rock concerts and have no issues. Eventually we all get older and will feel it eventually. Most people don't care until they get it.

 

Isn’t it suspected that it is neck and/or jaw injury/dysfunction that creates the environment for hyperacusis? Others without this condition just get hearing loss

There is an article in the hyperacusis section about it. I personally think the theory might be correct.

 

That didn't seem to be the case for me. My sensation of hyperacusis is definitely fading now after 6 months since it set in, following exposure to loud sound that also resulted in tinnitus. Seems only sound-induced, plus whatever stress I was under at that time (pre-COVID-19-vaccine, pandemic, early career scientist, what's there to be stressed about?).

 

When I first got tinnitus, I got hyperacusis to go along with it. The stress of having tinnitus was too much for me. Lots of anxiety... That will cause hyperacusis as well. As I got used the the tinnitus, the hyperacusis slowly went away.

My daughter has lots of anxiety and has hyperacusis to go along with it. She has little to no hearing loss. The theory is you feel anxiety and your body turns up the senses so you can hear the danger better. I guess it was useful for hearing predators a long long time ago. If your hyperacusis is the result of this, it will go away in time if you can get your anxiety under control. If it is due to neck/jaw issues, it probably won't.

 

Last time I spoke with Justin from Hough Ear Institute he told me they think that their pill will help with reducing inflammation of the inner ear as well as tinnitus. I hope HEI gets their act together for this pill. We’ll see soon if they are telling the truth.

 

You know I really think this is true for some people. I was told by the ENT that diagnosed my TMJ that my hyperacusis is likely related to my TMJ which was present when I got tinnitus and she said that a noise trauma can trigger these symptoms when TMJ is present but they can improve when it is treated. She said something about most ear pain especially in young people not being related to the ears and that TMJ also had a tendency to cause nerve inflammation and irritation in the ears therefore contributing to hyperacusis to some degree.

It turned out my chiropractor has a lot of experience treating TMJ and as soon as I started getting that treated by him along with my neck it took some off the edge of my hyperacusis although it didn't cure it by any means. It also made my ear pain a little less intense although it is still very much present.

 

Who would have thunk it? Hough Ear Institute has been discovered by Dr. Cliff.

The Hearing Loss Pill (NHPN-1010) | A New Cure...

 

I stumbled on below paper about Oblato and hearing loss / tinnitus pill NHPN-1010. If I read it correctly, the FDA approved compassionate use on patients:

FDA OKs expanded access program for HLB Therapeutics' tinnitus treatment candidate

It seems to me it is about the Hough Ear Institute pill. People from the United States may want to apply.

 

This looks like big news to me. Why isn't this news getting more attention?

 

OMG. This is a big deal, right? Do we know whether this is supposed to be a single round of treatments or something that we’d have to take on an ongoing basis?