Hough Ear Institute's Hair Cell Regeneration Project

Discussion in 'Research News' started by all to gain, Oct 2, 2019.

    1. tommyd87

      tommyd87 Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      tmj music
      They have quoted that the treatment cost would be about the cost of a hearing aid.

      At this stage, I think that would be a reasonable and plausible price point. We do not know exactly where that price point sits since it could be the cost of an expensive one (so $5K) or a cheap one (so $1K). It definitely won't be anywhere near the cost of what @weab00 noted of $267,120 or whatever it was.
       
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    2. Watasha
      No Mood

      Watasha Member Benefactor Advocate

      Tinnitus Since:
      03/2018
      Cause of Tinnitus:
      Unknown
      In the meantime, hop on over to this thread and take 3 minutes to email the American Tinnitus Association and ask them to use their recently received $2.7M bequest on funding research instead of call lines.

      Call to Action: Contact the ATA Right Now — 3 Minutes to Make a Difference

      The more paths for treatment, the more affordable it can be!
       
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    3. Sam99
      No Mood

      Sam99 Member

      Tinnitus Since:
      02/2020
      Cause of Tinnitus:
      Acoustic trauma/Loud noise for 3 hours straight.
      @weab00 was calculating price according to the price of HPN-07 on Sigma-Aldrich. It's not surprising considering they are notoriously known for their absurd pricing, I read somewhere they add up to 60x markup and even more on the chemicals they sell.

      So it will be much cheaper, although it will cost several thousands still.
       
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    4. Sam99
      No Mood

      Sam99 Member

      Tinnitus Since:
      02/2020
      Cause of Tinnitus:
      Acoustic trauma/Loud noise for 3 hours straight.
      I am not sure if this was posted before or not.

      This paper suggests that cochlear synaptopathy is more likely responsible for generation of tinnitus and hyperacusis rather than the death of sensory hearing cells.

      If that's the case then Hough Ear Institute's Pill or OTO-413 are more likely to reduce or eliminate tinnitus & hyperacusis than FX-322, at least in those with normal audiograms.

      @FGG

      Is noise-induced cochlear neuropathy key to the generation of hyperacusis or tinnitus?
       
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    5. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      It's not one thing. If it was always cochlear synaptopathy, hydrops wouldn't cause tinnitus. Neither would middle ear disease.

      Anything that interferes with the hearing signal will cause "phantom cochlea" i.e. tinnitus.

      It's not one structure.

      But cochlear synaptopathy is probably the most common cause in noise induced because the synapses are more sensitive to noise but it's not the only cause and a lot of people will have mixed hair cell loss and synaptopathy.
       
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