New University of Michigan Tinnitus Discovery — Signal Timing

Discussion in 'Research News' started by Hudson, Jun 20, 2013.

    1. Lucifer

      Lucifer Member Podcast Patron Benefactor

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Ear Infection
      By then maybe FX-322 may already be out. I think Susan Shore is going to continue to delay it and when regenerative hearing medicine comes out she will stop the trials.

      I feel like she is just milking the money and wasting it.
       
      • Agree Agree x 5
    2. PeterPan
      Nerdy

      PeterPan Member Advocate

      Location:
      Sydney
      Tinnitus Since:
      09/2016
      Cause of Tinnitus:
      Heat Exhaustion
      At least it looks like they are doing a very rigorous study!
       
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    3. Autumnly
      Wishful

      Autumnly Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Tinnitus Since:
      07/2013
      Cause of Tinnitus:
      noise-induced
      End of 2021? So I'm guessing it's unlikely that it'll be launched in 2022. Maybe 2023, 2024? So at least another three years of no improvements. I don't think I'll be able to endure that.
       
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    4. spedgas
      Gloomy

      spedgas Member Benefactor

      Tinnitus Since:
      09/2018
      Cause of Tinnitus:
      Unknown
      I appreciate her and her team. I understand she’s being thorough and doing it right, but every time she gives us a glimpse of a timeline it seems 6 months longer than the last estimate.
       
      • Agree Agree x 8
    5. OnceUponaTime
      Busy

      OnceUponaTime Member Podcast Patron Benefactor Hall of Fame Advocate

      Location:
      New York
      Tinnitus Since:
      11/11
      Cause of Tinnitus:
      Noise
      2021????:eek::eek::eek:
      And the waiting continues... sigh. :unsure::arghh:
       
      • Agree Agree x 4
    6. F-u-T

      F-u-T Member

      Location:
      AZ USA
      Tinnitus Since:
      10/2018
      Cause of Tinnitus:
      Acoustic Trama
      I say if it’s not out by end of 2021 we pull off an oceans 11 heist on Shore’s lab and commandeer some units.
       
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    7. Mathew Gould

      Mathew Gould Member Benefactor

      Tinnitus Since:
      6/2017
      Cause of Tinnitus:
      Neck/Jaw misalignment
      Why appreciate her? She's probably making hundreds of thousands of dollars a year. If someone held a gun to her head this device would have already been out and working. I guess she's been working on this device for 20 years.
       
    8. Mentos

      Mentos Member Benefactor

      Location:
      Cracow, Poland
      Tinnitus Since:
      03/2015
      Cause of Tinnitus:
      Noise induced, loud rock concert
      I am not sure what she meant by 2021, is it study completion or maybe FDA approval or even commercialization. The best case scenario is that she plans to finalize the study in 2020, get an FDA approval mid of 2021 and launch end of 2021.
       
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    9. BBakkers
      Tired

      BBakkers Member Podcast Patron Benefactor

      Location:
      Netherlands
      Tinnitus Since:
      2011, Spike 2019, Spike 2020
      Cause of Tinnitus:
      1e Loud Music, 2e earwax irrigation, 3e padel tennis
      I think we have better chance of FX-322 getting Compassionate Use (Expanded Access) in the meantime.
       
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    10. Mentos

      Mentos Member Benefactor

      Location:
      Cracow, Poland
      Tinnitus Since:
      03/2015
      Cause of Tinnitus:
      Noise induced, loud rock concert
      The thing is that if tinnitus is generated by cochlear synaptopathy then FX-322 may not help since it does not regenerate synapses. Shore's device might help in such cases or one of synaptopathy drugs (HEI pill, OTO-413, PIPE-505).
       
      • Agree Agree x 1
    11. BBakkers
      Tired

      BBakkers Member Podcast Patron Benefactor

      Location:
      Netherlands
      Tinnitus Since:
      2011, Spike 2019, Spike 2020
      Cause of Tinnitus:
      1e Loud Music, 2e earwax irrigation, 3e padel tennis
      True. Hopefully end of September we know more.
       
    12. Juan

      Juan Member

      Tinnitus Since:
      08/2014
      Cause of Tinnitus:
      Several causes
      The never ending story...
       
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    13. GlennS

      GlennS Member Podcast Patron Hall of Fame

      Tinnitus Since:
      1992
      Cause of Tinnitus:
      Loud music
      giphy.gif
       
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    14. DaveFromChicago

      DaveFromChicago Member Benefactor

      Tinnitus Since:
      01/2014
      Cause of Tinnitus:
      Headcold/Flu
      Samuel Beckett could have based "Waiting For Godot" on "Waiting For Susan Shore."
       
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    15. DaveFromChicago

      DaveFromChicago Member Benefactor

      Tinnitus Since:
      01/2014
      Cause of Tinnitus:
      Headcold/Flu
      Let me briefly elaborate further:
      It has been two and one half years since our Chicago Tribune in their Health and Wellness Section had a major article about how already a substantial amount of research and trial application on Shore's device had been completed.

      If this operates on at least a partially relational equivalence and methodology as Lenire, then why have they been able to make this available to the consumer for almost a year whereas Shore's might not be available until 2022?
       
    16. Amv

      Amv Member

      Tinnitus Since:
      16/7/2017
      Cause of Tinnitus:
      -
      I will always support anyone interested in helping us. In the meantime, we can hope Lenire can keep updating and improving its system and maybe Minnesota or any other company may launch another alternative...

      Let's hope Susan Shore can accelerate things up!
       
    17. Alex0o_o0
      Confused

      Alex0o_o0 Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      01/10/2018 - 04/04/2020
      Cause of Tinnitus:
      Whiplash/concussion - Sound trauma
      Hi all,

      So this Susan Shore Thing has apparently been building up for quite some time and people seem to place more value in her (hopefully) upcoming device than in Neuromod's Lenire device. However I do not seem to find any research that backs up the fact the Susan Shore's device would be any better than Neuromod's. Additionally Susan's Shore's research seems to be shrouded in vagueness and delayed deadlines.

      Can someone tell me where this bias towards Susan Shore is coming from? Is it based on actual scientific evidence, or just us sufferers clinging to the fact that the next thing coming out will be the actual cure?
       
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    18. GlennS

      GlennS Member Podcast Patron Hall of Fame

      Tinnitus Since:
      1992
      Cause of Tinnitus:
      Loud music
      I think it's less of a validation of Shore and more of a plan B because of Lenire disappointment.
       
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    19. F-u-T

      F-u-T Member

      Location:
      AZ USA
      Tinnitus Since:
      10/2018
      Cause of Tinnitus:
      Acoustic Trama
      The published results from the first Shore study seemed much better/more promising to me. 20 people were in the study and had an average 12 DB decrease in their T loudness. 2 people had T eliminated. No reports of any worsenings. The study was only 4 weeks of treatment. Pretty impressive results albeit a small sample size.
       
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    20. DoNotGoGentle

      DoNotGoGentle Member Benefactor

      Tinnitus Since:
      10/15 got worse 11/16
      Cause of Tinnitus:
      Earbuds, inner ear infection NHL and high frequency loss
      "The Neural Bases and Neuroengineering of...


      i know this was aleady posted from 2013. I would suspect it could take 8-10 years, until 2021 to 2023. She is super smart and this team is going to change the game. I have hope!
       
    21. danielbp85

      danielbp85 Member

      Tinnitus Since:
      12/2019
      Cause of Tinnitus:
      Hearing loss
      I wrote a short email to Dr. Shore to clarify the information that @Mentos has already got from her about the date of 2021. She replied

      "The 2nd trial should be done in the fall of 2020. I can't say exactly when commercialization will happen."

      So we can expect to see her results by the end of this year and maybe try the device late 2021 or early 2022.
       
      • Informative Informative x 6
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    22. UKBloke

      UKBloke Member Podcast Patron Benefactor

      Tinnitus Since:
      1991
      Cause of Tinnitus:
      Loud Music / family history
      I'm wondering whether it might be worth contacting the U-Mich office of tech transfer to try and get some idea of what the timeline to market can potentially be. Having said that, I'm not even sure there's much point until the trial data is made public.
       
    23. GlennS

      GlennS Member Podcast Patron Hall of Fame

      Tinnitus Since:
      1992
      Cause of Tinnitus:
      Loud music
      Apparently studies are like art--never finished, only abandoned. You have to know when you've reached the point of diminishing returns. It's a mindset, sort of like trying to cut a perfect circle out of a piece of paper.
       
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    24. mikki_

      mikki_ Member

      Tinnitus Since:
      07/2019
      Cause of Tinnitus:
      Stress / High frequency hearing loss
      She is a professor. They know shit about commercialization. Trust me I know. I hope a company like Neuromod buys the results. It will be much faster that way.
       
      • Agree Agree x 3
    25. davidmp

      davidmp Member

      Tinnitus Since:
      07/2019
      Cause of Tinnitus:
      Hearing Loss / Possible Trauma in concert
      I have made my mind: this is a life long battle, and have little hope for a solution that comes from anywhere in the coming years. I will have to fight it alone. I am not pessimistic, just optimistic with common sense.
       
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    26. sssing

      sssing Member Benefactor

      Tinnitus Since:
      2019
      Cause of Tinnitus:
      cold
      Thanks for the video but at the same time she’s just taking her own sweet time at the expense of all our suffering, if this thing really does work.
       
    27. sssing

      sssing Member Benefactor

      Tinnitus Since:
      2019
      Cause of Tinnitus:
      cold
      Why don’t you think one of these things coming up may help?
       
      • Good Question Good Question x 4
    28. DoNotGoGentle

      DoNotGoGentle Member Benefactor

      Tinnitus Since:
      10/15 got worse 11/16
      Cause of Tinnitus:
      Earbuds, inner ear infection NHL and high frequency loss
      She is taking her time because she wants this to work.
       
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    29. GlennS

      GlennS Member Podcast Patron Hall of Fame

      Tinnitus Since:
      1992
      Cause of Tinnitus:
      Loud music
      Or she feels no sense of urgency because... tenure.
       
      • Agree Agree x 6
    30. Fightthearmy

      Fightthearmy Member

      Tinnitus Since:
      2012
      Cause of Tinnitus:
      work-related
      Germinal! Germinal!
       

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