Vitamin Supplement (Nicotinamide Riboside) Successfully Prevents Noise-Induced Hearing Loss

Discussion in 'Treatments' started by exodus, Dec 2, 2014.

    1. juliob
      Confused

      juliob Member

      Location:
      Brazil
      Tinnitus Since:
      03/2018
      Cause of Tinnitus:
      Antidepressants / Loud Sound Exposure
      Thank you! It seems that undermethylation and the TMG usage wasn't a stressed topic. I guess @ZFire in other thread told me that as he uses an AD, undermethylation isn't a issue and I saw this argument elsewhere also I guess. I don't know anything about neurochemistry so I better schedule an appointment with a good functional doctor, but I know that I felt fine today using 200 mg of Niagen.
       
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    2. Seabert

      Seabert Member

      Location:
      Netherlands
      Tinnitus Since:
      2016
      Cause of Tinnitus:
      Unknown
      I have been a reader of this forum for a while now, and now decided to post on this subject.
      Since +/- 10 days I have been a daily supplement that includes 500mg NMN.
      I plan to take it for 2 months and report my findings here.

      Background:
      I am a 42 year old male. I have developed tinitus I around 6-7 years ago, at a very low level. I have no clear indication why, but probably due to hearing damage (i have visited many concerts when I was younger). About 5 years ago I suffered from acute hyperacusis due to an ear infection, which resulted in heavily distorted hearing at my right ear. (and also slight Meniere's disease) An audiogram at the doctor showed hearing damage in my right ear around the 1k Hz range. Whether or not this damage was pre-existing was impossible to tell. The doctors sent me home and said nothing else he could do.
      Luckily the hyperacusis has gone away in the +/- 6 months after that episode, but it was replaced with increased tinnitus.
      The last two years have been quite stressfull for me after the passing of a loved one, and I have noticed my tinnitus has increased over these years. In these years I have been drinking moderately but daily (2 units a day, sometimes more) and I have noticed I am clenching my jaws regularly (due to the stress).
      I currently (subjectively) class my tinnitus as a 6. It is a high pitched tone.
      As an example, I need to increase the volume of my TV to be able follow what is being said on the news over my tinnitus pitch.

      Regiment:
      Starting this January I decided "enough is enough" and I stopped drinking altogether. I also started to look for a good supplement that could increase my general health. This supplement I started taking about 10 days ago. I take it daily during my lunch, as I felt slighly nauseous taking it before breakfast.
      It was only recently that I noticed this thread, and the possible positive effects of NMN on hearing/tinnitus.

      So I decided to report on my findings on the effects in this thread.
      I will report today. At the 30 days mark, 45 days mark and the 60 days mark.
      Unfortunately I don't have a 0 day audiogram, as I only thought about doing all of on this forum yesterday.

      In addition I am going to check my hearing through a free tool online and post the audiograms here. I will use the exact same setup and settings each time I test. I would like to make a clear note that the results in the screencap seem to be a couple Db worse across the whole hearing range (due to lack of calibration) than the test I have done with the doctor 5 years ago.
      However, the test is intended to track changes over this period. And if there are any changes, the test will reflect that. Hopefully the results will be helpful to others.

      Supplement details:
      Nicotinamide Mononucleotide - 500mg
      Quercetin - 500mg
      Trans-Resveratrol - 400mg
      Astragalus - 200mg
      L-Theanine - 200mg
      Curcumin - 200mg
      Collagen - 100mg
      Crocin - 100mg
      Epogallocatechin Gallate - 100mg
      Fisetin - 100mg

      After 10 days of taking the supplement:
      Noticed Effects on Tinnitus: Subjective slight decrease of volume, and a slight increase in pitch/tone.
      Side effects: Slightly greasier skin, very slight dizzyness the first couple of days, muscles feel sometimes a bit tense.

      Audiogram
      As you can see, there is hearing damage especially in the right ear around the 1k Hz.
      Test 28th Jan.JPG
       
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    3. John Joseph

      John Joseph Member

      Tinnitus Since:
      05/2022
      Cause of Tinnitus:
      Acoustic Trauma
      @Seabert, any update?

      I've started taking this due to some positive results for high frequency losses of a couple people in this thread.
       
      • Informative Informative x 1
    4. vttbx

      vttbx Member Benefactor

      Location:
      Los Angeles
      Tinnitus Since:
      01/2001
      Cause of Tinnitus:
      Noise Induced
      @Seabert, I'm curious as to why you chose NMN over NR?
       
      • Good Question Good Question x 3
    5. Sam Marksmen
      Confused

      Sam Marksmen Member

      Tinnitus Since:
      06/2021
      Cause of Tinnitus:
      Meds
      Can anyone report back with severe tinnitus how Nicotinamide Riboside affected you?

      I'm worried about taking it as so many supplements can make tinnitus worse. This seems promising.
       
      • Good Question Good Question x 1
    6. ZFire
      Tired

      ZFire Member Podcast Patron Benefactor Hall of Fame

      Tinnitus Since:
      2012 (mild) & 04/2021 (severe)
      Cause of Tinnitus:
      Ototoxicity (2012) Unknown-likely noise induce (2021)
      I took it for about 6 months. It had no effect on tinnitus whatsoever.
       
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    7. GBB

      GBB Member Hall of Fame

      Location:
      NYC
      Tinnitus Since:
      2016-2019 (Mild, Cured) 8/2020 (Severe)
      Cause of Tinnitus:
      Virus / Microsuction / Acoustic Trauma
      No effect for me. Tried NR and NMN.
       
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    8. DebInAustralia
      No Mood

      DebInAustralia Member Benefactor Hall of Fame Advocate

      Location:
      Geelong, Victoria
      Tinnitus Since:
      12/2013
      Nicotinamide Riboside didn't do anything for my tinnitus either way.
       
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    9. Golly
      Bookworm

      Golly Member Benefactor

      Location:
      New York City
      Tinnitus Since:
      01/2011
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    10. SmallRonnie
      Ape-like

      SmallRonnie Member Podcast Patron Benefactor

      Location:
      Ireland
      Tinnitus Since:
      H since 2018. T since 2021
      Cause of Tinnitus:
      Loud noise
      That's kinda scary. I wonder how important this actually is. The supplement is very widely studied and it's possibly about to be banned as a supplement as it upgrades to drug status.

      Lots of stores have been pulling it recently.
       
    11. vttbx

      vttbx Member Benefactor

      Location:
      Los Angeles
      Tinnitus Since:
      01/2001
      Cause of Tinnitus:
      Noise Induced
      Debunked fairly well here:

      Longevity Supplement Increases Cancer Risk...
       
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    12. SmallRonnie
      Ape-like

      SmallRonnie Member Podcast Patron Benefactor

      Location:
      Ireland
      Tinnitus Since:
      H since 2018. T since 2021
      Cause of Tinnitus:
      Loud noise
      Very good! I just bought a bunch more NMN recently. It's so expensive too.
       
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    13. Halsy

      Halsy Member

      Location:
      Toronto
      Tinnitus Since:
      Sept. 2017
      Cause of Tinnitus:
      Abscess tooth
      While there's always the possibility a supplement may help, it's unlikely. And you should always be careful taking supplements to begin with. While they may be helping ABC, they can be harming XYZ at the same time. They can certainly damage liver and kidney function too.

      Take antioxidant boosters for example. Your body is all about homeostasis. If you flood it with antioxidants, it freaks out and thinks it's producing too much, so it stops. Then your antioxidant count plummets and takes about a full week to return to normal - barring you taking more antioxidants. In the same way that juice/smoothies sound really healthy - and they are tasty after all - they're really nutritionally deficient. You only actually get about 1%-2% of the nutritional benefit compared to if you had simply eaten the fruit/veggie whole. You're far better off just eating a (mostly) vegetarian diet and exercising regularly than you ever will taking supplements. Any doctor worth their salt will tell you that all most vitamins and supplements will do is make your pee more expensive. Barring some sort of genetic abnormality obviously.
       
    14. Lane

      Lane Member Hall of Fame

      Tinnitus Since:
      02/2018
      Cause of Tinnitus:
      Single 25 mg dose of (anticholinergic) drug Promethazine
      Most doctors know next to nothing about nutrition, and the therapeutic value of targeted supplementation. Just one example: They pay virtually no attention to Vitamin D levels, even though suboptimal Vitamin D levels is one of the most reliable indicators of how severe a COVID-19 infection will be. There are numerous other examples of life-transforming and life-saving nutrients that could be mentioned.

      Not necessarily trying to blame these doctors for their lack of knowledge, as they simply weren't taught anything about the critical importance of nutrition when going to medical school. And the medical schools don't teach it because they have no financial incentive to do so. We're left to our own devices to figure how to address nutritional deficiencies. Many people who've done so have saved their own lives from many different health conditions, including cancer.
       
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    15. TeslaGuy
      Studious

      TeslaGuy Member Benefactor

      Location:
      Finland
      Tinnitus Since:
      01/2008
      Cause of Tinnitus:
      Acoustic trauma
      Lol NMN was banned in the USA. I live in Europe and decided to try NMN. I have been feeling down lately and would need some energy boost to start exercising again.
       
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