Ketamine Relieves Depression By Restoring Brain Connections

Discussion in 'Research News' started by Nic B, Oct 5, 2012.

    1. wwtsai
      Assassinator

      wwtsai Member Podcast Patron Benefactor

      Location:
      San Francisco
      Tinnitus Since:
      Mild (2016) Bothersome (8/20)
      Cause of Tinnitus:
      SNHL
      • Agree Agree x 1
    2. Tezcatlipoca
      Question it

      Tezcatlipoca Member

      Location:
      Mexico
      Tinnitus Since:
      June 2020
      Cause of Tinnitus:
      NIHL
    3. Gb3

      Gb3 Member

      Tinnitus Since:
      12/19
      Cause of Tinnitus:
      Sshl
    4. Tezcatlipoca
      Question it

      Tezcatlipoca Member

      Location:
      Mexico
      Tinnitus Since:
      June 2020
      Cause of Tinnitus:
      NIHL
      It's an NDMA Receptor Antagonist.
       
    5. DaveFromChicago

      DaveFromChicago Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2014
      Cause of Tinnitus:
      Headcold/Flu
      Awhile ago I called my Primary Care Physician and requested a recommendation for a psychiatrist; I was notified that this COVID-19 shutdown engendered so many stress/depression related conditions (fear of contracting the virus, financial insecurity, enforced idleness and isolation that activated the level of paranoia exhibited in Munch's "The Scream") that I might well have to wait six months for an appointment.

      This was in fact corroborated by the comment in last month's Esquire Magazine that this and last year's sales of alcohol nationally have increased by 24%.

      But I'm with GBB; I am henceforth determined to try everything I can get.

      After all, it would not be unusual for one of these new drugs for depression by sheer serendipity to also remedy tinnitus.

      Recall that Depakote was originally developed for Epilepsy but was also found to be beneficial for migraines; Viagra was originally intended as a heart medication.
       
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    6. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Their website lists Ketamine as a related compound and Ketamime is available now:

      https://axsome.com/axs-pipeline/about-axs-05/

      Systemic NMDA antagonists work really well for some people but chronically especially there are risks.
       
    7. Jcmc

      Jcmc Member

      Tinnitus Since:
      11/2020
      Cause of Tinnitus:
      Very Loud Headphones!
      There are a lot of NMDA Receptor Antagonists in the market. I don’t see the first one to help tinnitus.
       
    8. kingsfan
      Mellow

      kingsfan Member

      Location:
      Southern California
      Tinnitus Since:
      Sep 17 '20 / Oct 20 '20 / Mar 31 '21
      Cause of Tinnitus:
      turning everything up to 11
      Dextromethorphan is an NMDA antagonist? That stuff always makes me feel absolutely terrible.
       
    9. Tezcatlipoca
      Question it

      Tezcatlipoca Member

      Location:
      Mexico
      Tinnitus Since:
      June 2020
      Cause of Tinnitus:
      NIHL
      I thought those risks were only in large doses over the span of years. Couldn't this be used episodically for relief? I think the effects were observed to last 6 weeks.
       
    10. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Yeah. Some people use Ketamine successfully that way and don't overdo it. Doesn't work for everyone but works very well for some people.
       
    11. Tezcatlipoca
      Question it

      Tezcatlipoca Member

      Location:
      Mexico
      Tinnitus Since:
      June 2020
      Cause of Tinnitus:
      NIHL
      Apparently it has Bupropion too. Doesn't that give tinnitus?
       
    12. Matchbox

      Matchbox Member

      Location:
      BC Canada
      Tinnitus Since:
      August 2020
      Cause of Tinnitus:
      Noise Induced, Prednisone (drones), Barotrauma (distortions)
      Yup I was mistaken.
       
    13. GlennS

      GlennS Member Podcast Patron Hall of Fame

      Tinnitus Since:
      1992
      Cause of Tinnitus:
      Loud music
      Here we go again ;)

      57spql.jpg
       
      • Funny Funny x 2
    14. Dolgoruki

      Dolgoruki Member Benefactor

      Location:
      United States
      Tinnitus Since:
      07/2020
      Cause of Tinnitus:
      Hearing loss
      Mind sharing the name of the Santa Monica clinic? That's where I live and was considering this option as well.
       
    15. Tezcatlipoca
      Question it

      Tezcatlipoca Member

      Location:
      Mexico
      Tinnitus Since:
      June 2020
      Cause of Tinnitus:
      NIHL
      Whatever helps lol.

      I'm actually much more hopeful on ebselen like most, but this one is going to be available imminently.
       
      • Funny Funny x 1
    16. kingsfan
      Mellow

      kingsfan Member

      Location:
      Southern California
      Tinnitus Since:
      Sep 17 '20 / Oct 20 '20 / Mar 31 '21
      Cause of Tinnitus:
      turning everything up to 11
      I don't remember the name, so googled "Santa Monica Ketamine infusion" and found 3 or 4 different places right in the first page of the SERPs.

      Looks like they are all around the Brentwood/Westwood/Marina Del Rey areas.
       
      • Like Like x 1
    17. Sentinel
      No Mood

      Sentinel Member

      Tinnitus Since:
      Late November/Early December 2020
      Cause of Tinnitus:
      Really epic hobbies
      Question is can I get my dickhead "just put on a fan" doctor to let me take it despite only being depressed because of the sound in my ear/head.

      I'm sure there's no data on if it helps tinnitus, but given the drug profile hopefully it does.
       
    18. Tezcatlipoca
      Question it

      Tezcatlipoca Member

      Location:
      Mexico
      Tinnitus Since:
      June 2020
      Cause of Tinnitus:
      NIHL
      Even if he wanted to, I don't think he could prescribe it to you. It's a very potent antidepressant, you most likely need to be diagnosed by a psychiatrist.

      I think out of any doctor the one easiest to trick would be a psychiatrist. IMO
       
    19. BuzzyBee
      Jaded

      BuzzyBee Member Benefactor

      Tinnitus Since:
      2016
      Cause of Tinnitus:
      Not Sure
      Thanks for the laugh! You should find a new doctor.

      But for the Ketamine, you'd need to talk to a psychiatrist and see if it's a fit. I doubt they'd prescribe it to you for just tinnitus, but if you have long term depression it might help.
       
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