Vitamin Supplement (Nicotinamide Riboside) Successfully Prevents Noise-Induced Hearing Loss

Discussion in 'Treatments' started by exodus, Dec 2, 2014.

    1. Heinrich_S7
      Psychedelic

      Heinrich_S7 Member

      Tinnitus Since:
      Uncertain
      Cause of Tinnitus:
      noise exposure
      Joe Rogan Experience #1234 - David Sinclair

      David Sinclair takes NMN/Resveratrol together. And if Sinclair does something, it's right.

      NR is a precursor molecule to NMN, there's literally no difference but the price. NR is better economically and it's also been tested for safety in humans. The only difference is NR acts as a prodrug to NMN.

      NMN is a waste of money since it’s far more expensive and just does the same thing. The only difference between them is your body converts NR into NMN, which then gets converted into NAD+

      I think David just takes it because he has a ton stored away from trials.
       
      • Informative Informative x 1
    2. Chriscom

      Chriscom Member Podcast Patron Benefactor

      Location:
      Northern Virginia USA
      Tinnitus Since:
      May 2019
      Cause of Tinnitus:
      Likely infection/ear stress after walking pneumonia
      Thought I would mention that I'd been taking NR (and Pterostilbene) for a good two years before I experienced sudden hearing loss and tinnitus, via Elysium's Basis supplement, which I haven't seen mentioned in this thread surprisingly. Not that I've read every single comment. The hearing loss/tinnitus arrived this spring, about a month after recovering from walking pneumonia though I'm told a link cannot be 100% established.

      I'd certainly like to think that the NAD+ precursor NR will slowly help me recover, at least somewhat, from these conditions, but during this period of course it hasn't.
       
      • Like Like x 1
    3. razo

      razo Member Podcast Patron Benefactor

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Audio exposure
      The Niacinamide 500mg I am using is about 1/10 of the price of NR. Why should I still buy NR?
      (Bear over with me as I am no pharmacist and value very much a few simple explanatory sentences).
       
      • Good Question Good Question x 2
    4. Heinrich_S7
      Psychedelic

      Heinrich_S7 Member

      Tinnitus Since:
      Uncertain
      Cause of Tinnitus:
      noise exposure
      Because Niacin doesn't raise NAD+ to any extent whatsoever.
       
      • Agree Agree x 1
    5. razo

      razo Member Podcast Patron Benefactor

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Audio exposure
      • Like Like x 2
    6. razo

      razo Member Podcast Patron Benefactor

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Audio exposure
      • Good Question Good Question x 1
    7. Jackjohnson183

      Jackjohnson183 Member Benefactor

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Ear wax removal
      For those of you taking NR at the moment. It’s usually 2 pills per day. Do you take both pills in the morning or do you separate the dosage like 1 pill in the morning and 1 pill at night?

      @Heinrich_S7 @vttbx @FGG
       
    8. FGG

      FGG Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Currently taking 2 pills twice a day here.
       
      • Like Like x 1
    9. Jackjohnson183

      Jackjohnson183 Member Benefactor

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Ear wax removal
      What time do you take the pills?
       
    10. FGG

      FGG Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      With breakfast and dinner. Varies a little day to day but between 7 to 9am for first dose and 6 to 8pm for second. I'm bad at being precise with my supplement timing, in general.
       
      • Like Like x 2
    11. Caveman

      Caveman Member

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Unknown
      So, have you had an audiogram to confirm your improvements?
       
      • Good Question Good Question x 2
    12. Donald King

      Donald King Member

      Tinnitus Since:
      1985
      Cause of Tinnitus:
      unknown
      I am 78 and have had continuous tinnitus for more than 35 years. I keep healthy by a keto diet, intermittent fasting and exercise. I have tried everything to reduce tinnitus - including sound therapy, TMJ work. all types of supplements,Vagus Nerve Stimulation etc.

      After reading David Sinclair's book "Lifespan Why we Age - and Why We Don't Have To" I started the protocol two weeks ago. 900mgs of NR and one gram of Resveratrol with a little oil every morning.

      Within a few days I noticed a dramatic increase in energy. And totally unexpectedly on the third day I suddenly noticed hearing blessed SILENCE, my tinnitus had vanished for the first time in 35 years!
      In the last 2 weeks it has briefly returned but soon disappears again. So I will keep monitoring it over the next months and years.

      Don
       
      • Informative Informative x 3
    13. FGG

      FGG Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Are you taking the 900mg of NR at once in the morning with your Resveratrol?
       
      • Informative Informative x 1
    14. vttbx

      vttbx Member Benefactor

      Tinnitus Since:
      01/2001
      Dr. Sinclair says the any of the NAD boosters can affect your sleep when taken in the evening. It does to me so I only take them in the morning.
       
      • Like Like x 1
    15. vttbx

      vttbx Member Benefactor

      Tinnitus Since:
      01/2001
      Interesting. I've never tried that high of a dosage NR. Are you taking it empty stomach plus oil?
       
    16. Jackjohnson183

      Jackjohnson183 Member Benefactor

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Ear wax removal
      I separate the dose because I’m worried about side effects but I may do this in the future and take both pills in the morning.
       
    17. MDrums

      MDrums Member

      Tinnitus Since:
      7/2017
      Cause of Tinnitus:
      Traumatismo acústico
      Hi!

      I have read the thread and I have a question. For this treatment, is it necessary to take 2 tablets of NR a day and another one of Resveratrol? Is it necessary to combine both or could I just take NR?

      Forgive my poor English :sorry:
       
    18. Mister Muso
      Busy

      Mister Muso Member

      Location:
      Scotland
      Tinnitus Since:
      2007 / April 2019
      Cause of Tinnitus:
      Loud music
      I think I'm going to abandon the half dozen supplements I've tried with no observable benefits, and start buying NR instead (along with my NAC)
       
      • Like Like x 1
    19. pinklights98
      No Mood

      pinklights98 Member

      Tinnitus Since:
      08/2016
      Cause of Tinnitus:
      Loud Noise Exposure
      I can say that this doesn't protect against hearing loss. I was on this for four months when a woman screamed in my ear, and I still got a threshold shift.

      Edit: I was actually taking around 500 mg a day with Resveratrol. Did not help me at all with tinnitus, and unfortunately didn't protect me from unexpected sounds. Still have aural fullness from the event which was over a week ago.
       
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    20. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown
      I stopped all other supplements about a week ago and started NR 2 days ago 300mg/daily. Yesterday was a a raging tinnitus day, today is as quiet as I get. I'll throw in updates as I go along.
       
      • Like Like x 2
    21. Jackjohnson183

      Jackjohnson183 Member Benefactor

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Ear wax removal
      I’ve also been noticing tinnitus fluctuations as well while taking NR. I think it could be a sign of healing and restoring.

      Do you take 2 tablets in the morning or do you separate the dosage.
       
    22. FGG

      FGG Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      No one knows (I don't think). I think we all take different doses.
       
    23. Fabrikat

      Fabrikat Member

      Tinnitus Since:
      1973
      Cause of Tinnitus:
      Otosclerosis then volume then viral infection
      But did it make you feel more youthful and energetic?
       
      • Good Question Good Question x 1
    24. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown
      I've got sleep issues so I am taking 2 tabs in the AM. Honestly my Tinnitus tends to go on 2-3 days bad peaking late in the cycle then moderating. So though this day is a good one, it is not unusual for me to experience fluctuations before starting NR.

      We'll see fingers crossed
       
      • Agree Agree x 1

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