Vitamin Supplement (Nicotinamide Riboside) Successfully Prevents Noise-Induced Hearing Loss

Discussion in 'Treatments' started by exodus, Dec 2, 2014.

    1. Heinrich_S7
      Psychedelic

      Heinrich_S7 Member

      Tinnitus Since:
      Uncertain
      Cause of Tinnitus:
      noise exposure
      I did actually, a couple months ago I switched over to Natural Factors.

      https://www.amazon.ca/gp/aw/d/B0037Z4Q8M?psc=1&ref=ppx_pop_mob_b_asin_image

      It’s a Canadian brand, I’m unsure if it’s available outside my home country. It has 250 Trans Resveratrol. Like Webber’s, it’s derived from Japanese Knotweed.
       
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    2. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      • Informative Informative x 2
    3. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown, viral?
      So I have something to report back about. I have had a significant improvement in my hearing since I began taking this. Ever since the viral attack damaged my hearing and caused my tinnitus I’ve had a notch of around 50-55 dB at 6 kHz. I could hear it if I when using various tone producing apps. I noticed about 3 weeks ago I could no longer find the notch. I just did an audiogram at my Neuromod assessment that showed it at 35 dB at 6 kHz. This improve the happened some 8 months after onset.
      No improvement in my tinnitus but the hearing thing is a big deal.

      Coincidence? Maybe.
       
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    4. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Well your OHCs improved but you still might have synaptic damage affecting your tinnitus. Still, that's awesome!
       
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    5. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown, viral?
      Help me out. What are OHCs?
       
      • Good Question Good Question x 1
    6. ajc

      ajc Member

      Tinnitus Since:
      11/2002; spike 2009; worse 2017-18
      Cause of Tinnitus:
      Loud music - noise damage
      Outer hair cells.
       
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    7. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown, viral?
      Is there any relationship between the healing of the OHC and recovery of whatever was damaged in the synaptic portion (I’m at a loss for the appropriate term)?
       
    8. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Probably? In terms of reducing the inflammation anyway. Sometimes damaged OHCs can recover if the damage isn't too severe (otherwise audiograms would never improve after SSHL). I don't see why the same wouldn't be true for synapses, though they don't tend to *directly* relate to each other (the synapses in "synaptopathy" are with the inner hair cells). I think reducing oxidative stress is key.
       
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      • Informative Informative x 1
    9. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      • Like Like x 1
    10. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      Read the thread and my head hurts... so people are still taking both Resveratrol and NR, or just NR?
       
    11. Gman
      No Mood

      Gman Member Benefactor

      Tinnitus Since:
      07/2016
      Cause of Tinnitus:
      Ototoxic earwax drops, worsened by MDs (Muppet Doctors)
      Mine contains NR, resveratrol, quercetin and betaine anhydrous all in one. I don't put a lot of faith in it, but just want to do all I can to protect myself.
       
      • Helpful Helpful x 2
    12. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      Wow NR is the most expensive supplement to date that I have seen.
       
      • Agree Agree x 3
    13. ajc

      ajc Member

      Tinnitus Since:
      11/2002; spike 2009; worse 2017-18
      Cause of Tinnitus:
      Loud music - noise damage
      It's too expensive if you want to take 300 mg per day.
       
    14. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      I’m still confused on what everyone uses on the dosages... one pill is 250mg, and I’ve seen “2 pills a day” to like 900mg... yikes.

      So it sounds like 500mg/day minimum, no?
       
    15. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      That's because no one knows who will benefit and what the correct dose would be. If you want a data point, I decided on 300mg twice daily eventually. But it's almost arbitrary that I picked that, honestly.
       
      • Helpful Helpful x 1
    16. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      Thank you.

      I wasn’t confused “why” anyone was using their levels, it wasn’t clear in reading the thread what the consensus was... which is good enough for me. :)

      My previous response was precipitated by “it's too expensive to take 300mg a day.” Which was a response to me saying it was the most expensive supplement I have encountered.

      I’m not sure if @ajc is trying to say 300mg is too much in their opinion?
       
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    17. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      I believe you felt that 600mg of the NR helped you? Are you taking Resveratrol as well?
      How about Lutein with Zeaxanthin?

      Can you be my pharmacist... lol sorry, you know a lot about this.
       
    18. FGG
      No Mood

      FGG Member Podcast Patron Benefactor Hall of Fame Advocate

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      I think NR helped me personally but I can't say that for sure or that it would help everyone. What it seemed to do for me is this: I have two high pitched tones: pure tone and cicadas. The pure tone was the louder and more intrusive of the two. It seemed to put the pure tone on the same level as the cicadas. I can't 100% say that NR (vs time, coincidence, etc because I was still fairly early) was what did it for me but it really seemed to. I did talk to someone else online (not here) who had tinnitus for a decade and said it made a dramatic difference for him. His was noise induced. It doesn't seem harmful for anything but the wallet so I think it's worth a try.

      I didn't start taking Resveratrol until months later nor the Astaxanthin. I do not take Lutein. I'm not sure Resveratrol is helping or doing anything really. But I'm not taking a whole lot. Other people say it helps. This is such an individual condition, who knows.

      Astaxanthin made music sound louder to me by about 10%. This happened in the first few weeks and then plateaued, unfortunately. I have kept those "gains" though so It was well worth it. It seemed to make my vision slightly sharper too, somehow (I can read signs earlier without the glasses i used to drive with). @Artazanasss seemed to have the same experience (he also has a good rationale for alternating it with Lutein). I believe we both had ototoxic damage so I'm not sure if that's part of why we had similar results. Fair warning, if you try this: Astaxanthin is why flamingos are pink. It might turn your stool red.
       
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    19. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      Lol red stool...I just had a work medical yesterday and was waiting for the question...”why is your urine specimen glowing flourescent yellow?” ;-). B complex, NAC, vitamins, Turmeric, etc....

      NR ...600mg?
      Astaxanthin...how much, guesstimate?

      I’ll try it for a month and see what happens...thanks.

      @alex1975 are. You still taking some combo of these, any results from September?
       
    20. BigNick

      BigNick Member Podcast Patron

      Tinnitus Since:
      11/2018
      Cause of Tinnitus:
      Unknown
      Sinclair has posted about hearing and resveratrol study Screenshot_20200209-124117.png
       
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    21. UKBloke

      UKBloke Member Podcast Patron Benefactor

      Tinnitus Since:
      1991
      Cause of Tinnitus:
      Loud Music / family history
      :LOL:
       
    22. MichaelSF

      MichaelSF Member

      Location:
      San Francisco Bay Area
      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Stress, Anxiety,
      Just ordered - and this stuff is not cheap - will update how it does for me, how long should I give it try? Usually I can tell if something helps with 10-14 days for me. Thanks for any input and/or suggestions.
       
    23. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown, viral?
      At about 5 weeks I noticed an improvement in my hearing
       
    24. MichaelSF

      MichaelSF Member

      Location:
      San Francisco Bay Area
      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Stress, Anxiety,
      Thank you. Great username btw :))
       
    25. InfiniteLoop
      Relaxed

      InfiniteLoop Member Benefactor

      Location:
      Redwood City, California
      Tinnitus Since:
      01/21/2014
      Cause of Tinnitus:
      Very high frequency hearing loss in left ear.
      I have been taking it for one year without changes in tinnitus or hearing.

      I am using Resveracel that contains NR (300mg) / Quercetin (250mg) / Trans-Resveratrol (150mg).

      @AfroSnowman Do you have audiograms showing the improvements or does this belong to the usual it cannot be checked and depending on the day I will give you a different answer.
       
    26. MichaelSF

      MichaelSF Member

      Location:
      San Francisco Bay Area
      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Stress, Anxiety,
      What dosage are you taking? Have you taken anything that’s had the same benefit or efficacy as your anti-fungal diet?
       
      • Good Question Good Question x 1
    27. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      Would you mind saying exactly the amount, brands, and dosages?

      Thanks.
       
    28. AfroSnowman
      Balanced

      AfroSnowman Member Podcast Patron Benefactor

      Tinnitus Since:
      April 16 2019
      Cause of Tinnitus:
      Unknown, viral?
      I am taking TRU Niagen at the 300mg/day recommended dosage.

      My story is that I had a sudden onset tinnitus with SSHL in the middle of the night last April. Based on the onset and symptoms ENT thinks it was viral. I had a noticeable gap at 6 kHz which measured at ~55 dB loss. This remained true for about 7 months. I would check my hearing at home now and again and could clearly hear the drop out at around 6 kHz. I tried this TRU Niagen and at about 5-6 weeks when doing my at home hearing test I could no long find the gap. I subsequently had an appointment with Lenire where they did a hearing test and sure enough the gap was gone and my hearing had recovered to around 35 dB at 6 kHz Could be a coincidence that it just took that long for healing to occur, but it was a good enough correlation for me to continue to pay the crazy price for the supplements. I'll keep on with these for at least a few more months and see whether any further improvements happen.
       
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    29. MRItechssuck
      Disappointed

      MRItechssuck Member

      Location:
      USA
      Tinnitus Since:
      Mild 2000-2018 sev 10/17/2019
      Cause of Tinnitus:
      Loud noise, MRI
      Are you also taking Resveratrol or just the TRU Niagen?

      I bought Astaxanthin when it was mentioned... but I can’t even remember who mentioned and whether it helped, sigh.
       
    30. ajc

      ajc Member

      Tinnitus Since:
      11/2002; spike 2009; worse 2017-18
      Cause of Tinnitus:
      Loud music - noise damage
      Astaxanthin helped @FGG I think...
       

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