Search results for query: potential-treatment-for-hyperacusis

Of course. Personally, I don’t think this is a silver bullet for typical, stable tinnitus. With new research emerging over the past year, it seems more likely to benefit reactive tinnitus, hyperacusis, and visual snow syndrome (VSS). This treatment appears to target the inferior colliculus (IC)...

Hey there! I'm trying to throw together an organized list of medications and supplements for people with hyperacusis to try. I've included short descriptions of each one and organized them by different categories of where the hyperacusis could be occurring (the inner ear, the middle ear, and...

I am fairly new to the tinnitus experience. Personally, I always assumed it was caused only by continuous exposure to excessively loud music or sudden, extremely loud events like gunshots or concerts. I thought gradual exposure would come with early warning signs, such as some degree of hearing...

Very good point, @ErikaS. In addition to sound that exacerbates tinnitus, how could electrical stimulation of the inner ear help reduce tinnitus that reacts to somatosensory input, such as jaw movement (TMJ disorder), cracking of the eustachian tubes, tension in the tensor muscle of the soft...

Authors: Anthony Nakamura (McDonald), Noxacusis Discord community, Gregg AKA Cranialboy Researchers Mentioned: S. Shore, T. Tzounopoulos, AJ Noreña, C Liu, PA Fuchs et al Introduction: Noxacusis, a debilitating auditory condition, emerges through a complex interplay of peripheral damage...

You are entitled to your views and opinions because I started this thread. You have highlighted the reasons why I believe keeping things simple with tinnitus, is the right approach and not to overcomplicate it with terminology such as reactive tinnitus, which at best is a subset of hyperacusis...

Wonder if people with hyperacusis will benefit from this?

Sorry for my ignorance, is it about spiral ganglions or an other nerve supplied zone ?

I think the goal is to remove those who are attempting to enter the trial for their tinnitus and not hearing loss. If the treatment is successful in treating hearing loss itself but the tinnitus crowd is unaffected, then the tinnitus crowd ruins the trial. It's clinically correct to try to fix...

Maybe Otologic will take it over. It does look promising though. I'd imagine there would be some VC who would like to fund it since it's already ahead of most other potential treatments in terms of development and everyone is rushing to be the first with a hearing loss/tinnitus/hyperacusis...

ps thank you for your kind words, I appreciate it. I am going to a tinnitus specialist audiologist and having an MRI separately with my ENT I have another ENT I am working with that has some potential treatment options like ear steroid injections etc... no clue what works or doesnt... Hard...

Originally, I was going to type a long post going over some things, but I have done this a million times before. It's useless, being an armchair scientist. This wasn't me before this affliction hit me. Instead, I will recommend a new alternative, but the people in power around here must take it...

Thanks for that Danny Boy. I may have misled by the mention of hyperacusis in reference to the proposed clinic treatments - I definitely don't suffer from that and would also be cautious of embarking on any drug related treatment with potential side effects, but the advice is nevertheless...

Good to see the suicidal thread take the direction of earmuffs fashion... we need a break. However, going back to @Jerad, This condition is diabolical precisely because of that. The same treatment or medication can have opposite effects on different people and this means that if you are...

This is an old post, but I was just reading about a drug called Ibudilast that is a powerful anti-inflammatory and also has potential to relieve pain via glial cell suppression. I was able to find one study where it was found to successfully reduce tinnitus, especially in those with high...

Hi Michael, I think it is unfair to categorize reading research as a negative activity. While I do agree that making baseless extrapolations of your own doom from mouse studies (which I assume is the sort of behaviour you’re referring to) does happen, most of the research people here engross...

- I appreciate those in this community who have a good eye to not only read studies such as this but analyze the information and then summarize it. Thank you for doing that as it helps with further understanding. - With the baseline time of tinnitus being 5-10 years, I personally find the...

Even if it’s Audion Therapeutics that comes out first I will most likely take it depending on what it gets rid of.

Hi dolpinskin, I am just extra cautious and may inform myself a little too much before receiving medical care! I think it's promising that a neurointerventional radiologist read your CTA to find venous sinus stenosis on your right side. Did they talk about placing a stent? I am of course not a...

Hello, everyone, My tinnitus started around August 20th, and at first, it was really mild. I could only notice it if I blocked my ears or was in a very quiet room. It sounded like an air-blowing or whooshing noise in my head and was easily maskable with a running fan. A week later, I visited...

This year, there were approximately 1700 people registered for the Association for Research in Otolaryngology (ARO) midwinter meeting held February 11- 15 in Orlando, Florida. Tinnitus research was presented in three of the sessions, which by itself seemed a good sign for a condition that...

Yup, I figured as much. Seems there’s always a catch with tinnitus and hyperacusis. My experience so far, at least. With treatments, trying something—anything—is really scary, to be honest... like playing a deadly game. You might get burned and you might get burned hard…to what extent is...

I think future treatments for hyperacusis could come from a number of different directions. I believe there's reason to be cautiously optimistic about the potential of therapies like FX-322 if approved. One of the leading theories is that painful hyperacusis in particular could arise from...

Although I have a very superficial understanding of this matter, I wonder why researchers haven't continued on this particular track of finding a cure to pain hyperacusis. To me, this sounds like the most promising area of a possible hyperacusis treatment, but I could be wrong. Why are there no...

Not seen you around in a while @Philip83. Hope you're keeping well and that the hearing aids are continuing to work for you. In any case, should you ever read this post, you can allay your fears (at least where the prospects are concerned): For while ACOU085 is designed to possibly treat...

I've been in the same boat with thinking I had hyperacusis only to finally find that my symptoms didn't fit what is thought to be the classical presentation. Hyperacusis, the way it is most commonly described seems to be a specific presentation of sound intolerance that is mostly about volume...

Thank you @jazz :) Yes I think I get it now. But it still doesnt answer how people can recover from hyperacusis (some even "cured") by TRT or other sound therapies. If the damage is permanent like tinnitus, it would not be able to get less hyperacustic? And in the past scientist has said that...

I could only find evidence for aspirin being ototoxic, not the other P2Y12 blockers. To be honest I am not really sure. I made this thread specifically for the P2Y12 receptor because it is the only one for which antagonists are readily available for us to try. Gefapixant, a P2X3 antagonist...

Questions: - Are your treatments targeted also for tinnitus and hyperacusis? - We understand that phase 1 trial is completed and was "extremely safe". While we acknowledge that Phase 1 is meant to test the safety of the medication, what were the results on hearing loss, tinnitus and...

I'm glad you're feeling much better. What dosage of Anafranil and Quetiapine did you find helped most? Could you attend concerts with earplugs? Did you have any hyperacusis in the early years? If so, how is the hyperacusis today?

I'm also really interested to hear how it went! I'm actually contemplating getting in touch with Myriam Westcott as she seems very sympathetic and keen to discuss her work. One thing I'm sort of unclear on is whether the SGB would be recommended for pain caused by acoustic shock disorder or...

Sorry but that sounds like total bollocks. "Flupirtine exhibits efficacy on all four subunits, Kv7.2, Kv7.3, Kv7.4 and Kv7.5, with an apparent preference for Kv7.3... Reduction in Kv7.2 and Kv7.3 channel activity leading to hyperactivity in the dorsal cochlear nucleus (an auditory brainstem...

They most likely know about tinnitus reduction happening from patients taking Trobalt in the past. Whether they want to test it on tinnitus patients is up to them. Obviously with the number of people suffering from tinnitus in recent times it’s a no brainer that they should test XEN1101 and...

It does not sound severe to me, actually pretty normal. Certainly, this can be very frightening, but most people do recover. I hope you have started your antibiotics to address any potential medical issues. I would also continue to be very careful with noise exposure for the first month (and...

I think I'll treat the background I have and my own research as trumping your wall of text on the subject. One PDF you definitely didn't take the time to digest doesn't really mean much... I've kinda obsessed about it as this is obviously hell to deal with. But I would rather not end up dead...

A review of auditory gain, low-level noise and sound therapy for tinnitus and hyperacusis Abstract Objective: This article reviews: (1) the evidence related to enhanced central gain as a potential mechanism for the generation of tinnitus and hyperacusis, (2) the neuroplastic changes induced by...

@Uklawyer, thanks! I started in July but I only did it a couple times in July/August. For the last 4 or 5 weeks I have been doing it weekly. Tinnitus volume was maybe a 5 or 6 with pretty sensitive hyparacusis (for example, water turned on too strong hitting the sink would hurt my ears, I also...

I really wish they would test hyperacusis too! Maybe eventually...

I'm currently going through a relapse in pain hyperacusis after being free of it for 5 months, although had tinnitus all that time still. I got this relapse after an MRI even though I was wearing earplugs. Do you think it would be possible for me to ever go to a bar/nightclub again wearing...

The issue is, people don't look at the hyperacusis thread...So seriously, you've got an issue about me trying to help people? Do you think I make money off a generic drug? Don't think so, take a chill pill mate. I'll take 10000% slack if I can treat or cure another person's hyperacusis, as I...

Ditto, my hyperacusis is reasonably down and once there's a cure for that and my hearing I'll never step foot in an overly loud environment like a club especially without hearing protection ever again. I tossed all of my headphones, I still listen to music but nothing over 60 dB, though I prefer...

HI @BarbaraZ Wearing an earplug or plugs to suppress external sound because you have hyperacusis will not cure your problem, which is over sensitivity to sound. Whilst this may yield some benefits you are creating more problems for yourself in the long term, as a lowering of the "loudness...

I need some help trying to understand the method of action of certain pharmaceutical products. If there are any biochemists, chemists, deep-dive researchers out there, please chip in! For months now I've been following a line of thought. Is the cure to tinnitus and hyperacusis already out...

Hard Agree. This is why academics, researchers, companies, CEOs, etc, setup Q&A events or interviews with people like those running the TinnitusTalk Podcast. They are establishing an appropriate forum for potential patients / customers / doctors / investors, etc to ask questions and get...

Thanks for the insights, Mark! Update: The feeling of fullness in my ears is still present, although it changes sometimes. I’m not sure if that’s because I’m distracted or if it’s actually getting better. It’s definitely worse in the evenings when the fullness becomes extreme, so I use...

I feel the same way, even after more than two years into my worsening of tinnitus, which later included hyperacusis and TTTS. I already had moderate hearing loss. The severe tinnitus is the worst of those for me, which causes anxiety and insomnia. There's never a good age to be hit with these...

I'm sorry to hear about your experience, and would imagine all of us with tinnitus have experienced that to some extent. However, fundamentally, I believe that doctors want to help their patients, and I've talked to a number of them who are very excited about the potential of all these drugs in...

Perhaps Neuromod must, after all those ENT congress presentations in the US, convince the local ENTs to establish the treatment for the potential patients. I guess they didn't do this before and this is the reason why they are so busy and silent. It takes a lot of time for all the contract...

It baffles me that a potential treatment could be on the way before we have even found a way to reliably diagnose these auditory problems. I had good speech in noise scores, yet I have the feeling I often hear without understanding. Never mind acoustic reflex testing. I heard that's loud, so a...

Hi, Recently I've regrettably developed mild hyperacusis as a delayed onset from a concert that I attended a month ago (even though I wore earplugs), which also spiked my tinnitus, but didn't result in any hearing loss. Right now, even a single car or two that pass by me at medium speed sound...

Hi @Lane - I think you misunderstood. Yes, they can cause tinnitus but antidepressants, as far as I am aware, have nothing to do with hearing loss. Tinnitus is a side effect of many of them indeed and yes sometimes it stays even after stopping taking them, but just because tinnitus is developed...

Hey @Pixelito. Thank you for your support. I envy you your optimism. Me, I still cannot believe I stepped onto the mine called tinnitus/hyperacusis. So avoidable. If I had only researched the topic of misophonia (from which I suffered) better, I would have learned about tinnitus/hyperacusis and...

@Srebint Please read my article in the link that I sent you titled: Hyperacusis As I see it. I will paste the link below. In it I explain about the use of earplugs. They shouldn't be over used. I do not agree with what your ENT doctor is advising you but it is your choice. I cannot know how...

I can never imagine the hell you're going through. I have pretty bad sound sensitivity and reactivity of the tinnitus, but not to the extent you're describing, but I have loads of sympathy for you, and do know I sincerely hope the best for you. Please forgive me for this thoughtless question...

As far as I can tell, the only drawback seems to be potential minor loss of hearing in the higher frequencies. But it's minor to the point that subjects don't notice it unless they take a PTA, i.e. no subjectively perceived loss of hearing. Also, I'm pretty sure this only applies to the round...

I don't think hyperacusis is best treated by desensitizing or normalizing hearing. I think this is what professionals say when they have no knowledge of the cause of hyperacusis and can offer no real treatment. I think hyperacusis may be a completely natural result of damaged hearing, and that...

Yes, the noise insult seems to cause some kind of neurological anxiety/stress response, causing the middle-ear muscles to involuntarily contract and spasm in anticipation of new potential loud noise. In that sense it is some kind of post-traumatic stress. This is controlled by the autonomous...

Let's put this in perspective: Oxygen = free radicals. Pressure = barotrauma. Together = potential for mechanical impaction / fistula, and even MORE free radicals. Oh and oxygen is a stimulant, so nerves will fire even more (more radical formation). HBOT makes a lot of sense if you're having...

Fournier and Noreña recently released an interesting paper that somewhat follows up their 2018 acoustic shock study. In the study, one of the patients reported getting a botox injection into their tensor tympani muscle (TTM) which they described as a "complete success": "The patient recently...

Don't listen to your doctor. Stay away from taking any drugs as much as you can. Especially benzos or antidepressants. Staying clean is the best option for tinnitus. I am also wondering if Dr. Shore's device can help people with reactive tinnitus and hyperacusis. Not sure I'll be around to use...